Dichlorobis(tri-o-tolylphosphine)palladium(II)
Product Information
Molecular Formula
PdCl2[P(CH3C6H4)3]2
Molecular Weight
786.06
Description
Application Guide for Palladium Catalyzed Cross-Coupling ReactionsCatalyst for C-C and C-N coupling reaction.
Dichlorobis(tri-o-tolylphosphine)palladium(II) has been employed as catalyst for the following studies:• Reaction of tributyltin enolates, prepared in situ from tributyltin methoxide and enol acetates, with aryl bromides.• Coupling reaction of aryl bromides with vinylic acetates.• Negishi-Reformatsky coupling reaction of aryl bromides with ethyl 2-(tributylstannyl)acetates.• Synthesis of (E)-methyl 3-(7-indolyl)-2-methacrylate, via Heck reaction.• Synthesis of imidazopyrimidine derivatives.
Dichlorobis(tri-o-tolylphosphine)palladium(II) has been employed as catalyst for the following studies:• Reaction of tributyltin enolates, prepared in situ from tributyltin methoxide and enol acetates, with aryl bromides.• Coupling reaction of aryl bromides with vinylic acetates.• Negishi-Reformatsky coupling reaction of aryl bromides with ethyl 2-(tributylstannyl)acetates.• Synthesis of (E)-methyl 3-(7-indolyl)-2-methacrylate, via Heck reaction.• Synthesis of imidazopyrimidine derivatives.
Synonyms
PdCl2[P(o-Tol)3]2
IUPAC Name
dichloropalladiumtris(2-methylphenyl)phosphane
SMILES
CC1=CC=CC=C1P(C2=CC=CC=C2C)C3=CC=CC=C3C.CC1=CC=CC=C1P(C2=CC=CC=C2C)C3=CC=CC=C3C.Cl[Pd]Cl
InChI
InChI=1S/2C21H21P.2ClH.Pd/c2*1-16-10-4-7-13-19(16)22(20-14-8-5-11-17(20)2)21-15-9-6-12-18(21)3/h2*4-15H,1-3H32*1H/q+2/p-2
InChI Key
OTYPIDNRISCWQY-UHFFFAOYSA-L
Melting Point
280 °C (dec.) (lit.)
Flash Point
Not applicable
Purity
97%
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
0
Rotatable Bond Count
6
Exact Mass
784.11736 g/mol
Monoisotopic Mass
784.11736 g/mol
Topological Polar Surface Area
0Ų
Heavy Atom Count
47
Formal Charge
0
Complexity
289
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
3
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| JP-2022042002-A | Fluorene compound and its manufacturing method | 2020-08-31 |
| JP-2022040080-A | Fluorene derivatives and resins and their manufacturing methods and applications | 2020-08-28 |
| WO-2022026500-A1 | Substituted haloalkyl sulfonanilide herbicides | 2020-07-29 |
| WO-2022012622-A1 | Degradation of (egfr) by conjugation of egfr inhibitors with e3 ligase ligand and methods of use | 2020-07-16 |
| US-2022009924-A1 | Modulators of thr-beta and methods of use thereof | 2020-07-10 |
| WO-2022011120-A1 | MODULATORS OF THR-β AND METHODS OF USE THEREOF | 2020-07-10 |
| WO-2022003510-A1 | Triazolopyridine compounds useful as pesticides | 2020-06-29 |
| WO-2021255052-A1 | Process for making a conjugated diene from an allyl alcohol | 2020-06-17 |
| JP-2020117517-A | Method for producing 2-amino-1-(pyridin-2-yl)ethanone compound | 2020-03-30 |
| CN-111303151-A | Aza, oxa, mixed nitrogen/oxa-hydrogenated annulated [ n ] arenes and preparation method thereof | 2020-03-04 |
