Dichlorobis(trimethylphosphine)nickel(II)
Product Information
Molecular Formula
[((CH3)3P)]2NICl2
Molecular Weight
281.75
Description
Catalyst for:• Wenkert arylation of thiophene with aryl Grignard reagents• Regioselective [2+2+2] cycloaddition of carboryne with alkynes to give benzocarborane compounds• Kumada-Corriu cross coupling of Grignard reagents• Borylation of aryl chlorides• Reductive aldol cyclization-lactonization• Arylcyanation of alkynes• Alkynylation of benzonitriles via C-C bond activation
Synonyms
Bis(trimethylphosphine)nickel dichloride
IUPAC Name
dichloronickeltrimethylphosphane
SMILES
CP(C)C.CP(C)C.Cl[Ni]Cl
InChI
InChI=1S/2C3H9P.2ClH.Ni/c2*1-4(2)3/h2*1-3H32*1H/q+2/p-2
InChI Key
KYHNNWWCXIOTKC-UHFFFAOYSA-L
Melting Point
194-199 °C (lit.)
Flash Point
Not applicable
Purity
97%
Safety Information
Hazards
H302 + H312 + H332
Precautionary Statement
P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
0
Rotatable Bond Count
0
Exact Mass
279.961422 g/mol
Monoisotopic Mass
279.961422 g/mol
Topological Polar Surface Area
0Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
10.8
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
3
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CA-3032734-A1 | Methods for cross coupling | 2016-08-23 |
| EP-3504217-A1 | Methods for cross coupling | 2016-08-23 |
| JP-2019528296-A | Cross coupling method | 2016-08-23 |
| KR-20190041485-A | Cross coupling method | 2016-08-23 |
| US-2019202769-A1 | Methods for cross coupling | 2016-08-23 |
| WO-2018039232-A1 | Methods for cross coupling | 2016-08-23 |
| RU-2019104463-A | METHODS OF CROSS COMBINATION | 2016-08-23 |
| US-10793504-B2 | Methods for cross coupling | 2016-08-23 |
| CN-109661399-B | Cross-coupling method | 2016-08-23 |
| WO-2017177921-A1 | Liquid crystal polyester composition | 2016-04-13 |
