Diphenyltin dichloride
Product Information
Molecular Formula
C12H10Cl2Sn
Molecular Weight
343.82
Description
Diphenyltin dichloride is an eminent compound within the biomedical realm. As an organometallic reagent, its uninhibited utility manifests during pharmaceutical drug synthesis. Employed diligently in combatting formidable maladies like cancer and fungal infections, its multifaceted nature garners profound admiration.
Synonyms
Dichlorodiphenyltin
IUPAC Name
dichloro(diphenyl)stannane
SMILES
C1=CC=C(C=C1)[Sn](C2=CC=CC=C2)(Cl)Cl
InChI
InChI=1S/2C6H5.2ClH.Sn/c2*1-2-4-6-5-3-1;;;/h2*1-5H;2*1H;/q;;;;+2/p-2
InChI Key
ISXUHJXWYNONDI-UHFFFAOYSA-L
Boiling Point
333-337°C
Melting Point
41-43°C
Flash Point
235.4 °F - closed cup
Purity
95%
Appearance
white to off-white crystalline powder
Safety Information
Hazards
H302 + H312 + H332 - H315 - H319 - H335 - H400
Precautionary Statement
P273 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
0
Rotatable Bond Count
2
Exact Mass
343.918158 g/mol
Monoisotopic Mass
343.918158 g/mol
Topological Polar Surface Area
0Ų
Heavy Atom Count
15
Formal Charge
0
Complexity
174
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113816988-A | Synthetic method of triphenyl tin acetate | 2021-10-25 |
| CN-113637296-A | Preparation method of polylactic acid composite material and preparation method of degradable optical film | 2021-07-01 |
| CN-113025379-A | Coking inhibitor for advanced catalytic cracking olefin preparation device and preparation method thereof | 2021-02-04 |
| CN-114057913-A | Solid catalyst component for olefin polymerization | 2020-08-07 |
| JP-2022031142-A | Solid catalyst component for olefin polymerization | 2020-08-07 |
| US-2022041763-A1 | Solid catalyst component for olefin polymerization | 2020-08-07 |
| CN-111926313-A | Composite material of metal zinc foil and zinc-philic crystal nucleus and preparation method and application thereof | 2020-08-05 |
| CN-111926313-B | Composite material of metal zinc foil and zinc-philic crystal nucleus and preparation method and application thereof | 2020-08-05 |
| CN-113999276-A | Purification method and preparation method of deacetyl hairy flower glycoside intermediate | 2020-07-28 |
| CN-111766319-A | Method for simultaneously determining contents of tin and lead in different forms in tobacco | 2020-07-14 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 31706034 | 2020-02-01 | Interaction of organotin compounds with three major glutathione S-transferases in zebrafish | Toxicology in vitro : an international journal published in association with BIBRA |
| 20184325 | 2010-03-25 | Identification of inhibitors of drug-resistant Candida albicans strains from a library of bicyclic peptidomimetic compounds | Journal of medicinal chemistry |
| 19959261 | 2010-03-01 | Synthesis, characterization and biocidal activity of new organotin complexes of 2-(3-oxocyclohex-1-enyl)benzoic acid | European journal of medicinal chemistry |
| 19497422 | 2009-07-15 | Structure-dependent activation of peroxisome proliferator-activated receptor (PPAR) gamma by organotin compounds | Chemico-biological interactions |
| 17002447 | 2006-10-04 | Antioxidative effect of quercetin and its equimolar mixtures with phenyltin compounds on liposome membranes | Journal of agricultural and food chemistry |
| 15941851 | 2005-10-01 | Trialkyltin compounds bind retinoid X receptor to alter human placental endocrine functions | Molecular endocrinology (Baltimore, Md.) |
| 15881455 | 2005-04-22 | New approach of solid-phase microextraction improving the extraction yield of butyl and phenyltin compounds by combining the effects of pressure and type of agitation | Journal of chromatography. A |
| 16705815 | 2005-04-01 | Synthesis and structure-activity correlation studies of metal complexes of alpha-N-heterocyclic carboxaldehyde thiosemicarbazones in Shewanella oneidensis | International journal of environmental research and public health |
| 12128105 | 2002-05-01 | Suppression of uterine decidualization correlated with reduction in serum progesterone levels as a cause of preimplantation embryonic loss induced by diphenyltin in rats | Reproductive toxicology (Elmsford, N.Y.) |
| 5842 | 1976-05-01 | Bile canalicular alkaline phosphatase and disease | Acta pathologica et microbiologica Scandinavica. Section A, Pathology |
