EPhos Pd G4
Product Information
Molecular Formula
C50H70NO4PPdS
Molecular Weight
918.55
Description
Buchwald palladacycle precatalyst with EPhos ligand for Pd-catalyzed C-N cross-coupling between primary amines and aryl halides to form 2-arylaminooxazoles. Catalyst system was reported with NaOPh (CDS001581).It is a fourth generation (G4) Buchwald precatalyst that is similar to the third generation (G3) precatalysts except that the amino group on the biphenyl backbone is methylated. This modification helps to prevent the limitations of using the third generation precatalysts. It is air, moisture and thermally-stable and shows good solubility in common organic solvents. BrettPhos Pd G4 is highly useful in cross-coupling reactions. Some of its excellent features include lower catalyst loadings, shorter reaction time, and efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.
Flash Point
Not applicable