Glutaric anhydride
Product Information
Molecular Formula
C5H6O3
Molecular Weight
114.1
Description
Glutaric anhydride is a cyclic dicarboxylic anhydride that is oxane which carries oxo groups at positions 2 and 6. It is used as an intermediate in the production of pharmaceuticals, corrosion inhibitors, and polymers (E.g. epoxy polyesters). It is a cyclic dicarboxylic anhydride and a member of oxanes. It is functionally related to a glutaric acid.
Synonyms
2H-Pyran-2,6(3H)-dione,dihydro-; 6(3H)-dione,dihydro-2H-Pyran-2; Anhydrid kyseliny glutarove; anhydridkyselinyglutarove; dihydro-2h-pyran-6(3h)-dione; Glutaric acid anhydride
IUPAC Name
oxane-2,6-dione
SMILES
C1CC(=O)OC(=O)C1
InChI
InChI=1S/C5H6O3/c6-4-2-1-3-5(7)8-4/h1-3H2
InChI Key
VANNPISTIUFMLH-UHFFFAOYSA-N
Boiling Point
290°C(570.076 torr)
Melting Point
55-57°C
Flash Point
347.0 °CF
Purity
MP 54-56deg
Density
1.24
Appearance
beige to light brown crystalline powder
Application
Used to make fine chemicals.
Storage
2-8°C
Safety Information
Hazards
H302 - H315 - H318
Precautionary Statement
P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310
Computed Properties
XLogP3
-0.1
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
0
Exact Mass
114.031694049 g/mol
Monoisotopic Mass
114.031694049 g/mol
Topological Polar Surface Area
43.4Ų
Heavy Atom Count
8
Formal Charge
0
Complexity
114
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114010798-A | Enzymatic self-assembly and disassembly curcumin drug-loaded hydrogel precursor and application thereof | 2021-12-27 |
| CN-114181384-A | Low-cost, pinhole-resistant and high-hardness polyester resin for HAA system and preparation method thereof | 2021-12-20 |
| CN-114106571-A | Polymer material for rapidly repairing asphalt pavement cracks and preparation method thereof | 2021-12-14 |
| CN-114163547-A | Pharmaceutical composition for mild photothermal treatment of tumors and preparation method and application thereof | 2021-12-14 |
| CN-114106651-A | High-temperature-resistant fluorine-silicon coating and preparation method thereof | 2021-12-13 |
| JP-2022027821-A | Fibrous Cellulose-Containing Compositions and Paints | 2021-12-01 |
| CN-114133466-A | Chitosan derivative used for food preservation and preparation method thereof | 2021-11-29 |
| CN-114014774-A | Fluoroamidone artificial hapten, artificial antigen, and preparation method and application thereof | 2021-11-23 |
| CN-113979980-A | Preparation method of high-purity butyrolactone | 2021-11-22 |
| CN-114133433-A | Protein tag, fusion protein or labeled conjugate containing protein tag and application of protein tag | 2021-11-22 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22569546 | 2012-06-14 | Disulfide- and terminal alkyne-functionalized magnetic silica particles for enrichment of azido glycopeptides | Chemical communications (Cambridge, England) |
| 22339049 | 2012-03-02 | Catalytic enantioselective desymmetrization of meso-glutaric anhydrides using a stable Ni2-Schiff base catalyst | Organic letters |
| 22122759 | 2012-01-11 | Development and application of an indirect competitive enzyme-linked immunosorbent assay for the detection of p,p'-DDE in human milk and comparison of the results against GC-ECD | Journal of agricultural and food chemistry |
| 22158441 | 2011-12-13 | Tandem synthesis of alternating polyesters from renewable resources | Nature communications |
| 22215983 | 2011-12-01 | Mitotic spindle assembly around RCC1-coated beads in Xenopus egg extracts | PLoS biology |
| 21667932 | 2011-07-18 | Macrobicyclic cage amine ligands for copper radiopharmaceuticals: a single bivalent cage amine containing two Lys3-bombesin targeting peptides | Inorganic chemistry |
| 22224094 | 2011-07-01 | Development and validation of a rapid HPLC method for simultaneous analysis of budesonide and its novel synthesized hemiesters in colon specific formulations | Research in pharmaceutical sciences |
| 21623496 | 2011-06-01 | Design and characterization of a direct ELISA for the detection and quantification of leucomalachite green | Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment |
| 20429772 | 2011-02-01 | Preparation of budesonide-dextran conjugates using glutarate spacer as a colon-targeted drug delivery system: in vitro/in vivo evaluation in induced ulcerative colitis | Journal of drug targeting |
| 22007170 | 2011-01-01 | From understanding cellular function to novel drug discovery: the role of planar patch-clamp array chip technology | Frontiers in pharmacology |
