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Tertiary Amine
Glycine,N,N-bis[2-(2,6-dioxo-4-morpholinyl)ethyl]-

Glycine,N,N-bis[2-(2,6-dioxo-4-morpholinyl)ethyl]-

Inquiry

Molecular Formula:

C14H19 N3 O8

Molecular Weight:

357.32

CAS Number:

23911-26-4

Catalog Number:

23911-26-4

Product Information

Molecular Formula:

C14H19 N3 O8

Molecular Weight:

357.32

Description

Glycine, N,N-bis[2-(2,6-dioxo-4-morpholinyl)ethyl]- is a multifaceted compound of immense significance and finds extensive application within the realm of biomedicine. Prominently employed as a pivotal constituent in pharmaceutical formulations, this compound exhibits remarkable efficacy when combatting diverse afflictions encompassing cancer, diabetes, and neurological disorders. Its pharmacological potential propels it to the forefront of drug discovery and therapeutic interventions, solidifying its indispensable status within the realm of biomedicine.

Synonyms

N,N-BIS[2-(2,6-DIOXOMORPHOLINO)ETHYL]GLYCINE; DIETHYLENETRIAMINEPENTAACETIC ACID ANHYDRIDE; DIETHYLENETRIAMINEPENTAACETIC ANHYDRIDE; DIETHYLENETRIAMINEPENTAACETIC DIANHYDRIDE; DIETHYLENETRIAMINE-N,N,N',N'',N''-PENTAACETIC ACID ANHYDRIDE; DIETHYLENETRIAMINEPEN

IUPAC Name

2-[bis[2-(2,6-dioxomorpholin-4-yl)ethyl]amino]acetic acid

Canonical SMILES

C1C(=O)OC(=O)CN1CCN(CCN2CC(=O)OC(=O)C2)CC(=O)O

InChI

InChI=1S/C14H19N3O8/c18-10(19)5-15(1-3-16-6-11(20)24-12(21)7-16)2-4-17-8-13(22)25-14(23)9-17/h1-9H2,(H,18,19)

InChI Key

RAZLJUXJEOEYAM-UHFFFAOYSA-N

Boiling Point

656.2ºC at 760 mmHg

Melting Point

190-184ºC

Purity

>98.0%(T)

Density

1.46g/cm3

Appearance

white or cream white solid

Storage

−20°C

Safety Information

Hazards

H315:
Causes skin irritation.
H319:
Causes serious eye irritation.

Precautionary Statement

P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].

Computed Properties

XLogP3

-3.3

Hydrogen Bond Donor Count

Hydrogen Bond Acceptor Count

Rotatable Bond Count

Exact Mass

357.11721457 g/mol

Monoisotopic Mass

357.11721457 g/mol

Topological Polar Surface Area

134Å²

Heavy Atom Count

Formal Charge

Complexity

504

Isotope Atom Count

Defined Atom Stereocenter Count

Undefined Atom Stereocenter Count

Defined Bond Stereocenter Count

Undefined Bond Stereocenter Count

Covalently-Bonded Unit Count

Compound Is Canonicalized

Yes

Patents

Publication Number	Title	Priority Date
CN-114042439-A	Uranium-containing wastewater adsorbent and preparation method thereof	2021-12-15
CN-113209304-A	Chelated calcium self-assembled nano particle and preparation method and application thereof	2021-05-19
CN-113234442-A	Paramagnetic chiral graphene quantum dot and preparation method and application thereof	2021-05-11
CN-113509562-A	Formulations comprising PD-L1 binding polypeptide compositions and methods of making the same	2021-04-22
CN-113057411-A	Anti-skid shoe sole for women and preparation process of anti-skid shoe sole	2021-04-13
CN-112741837-A	Brain-targeting nano-drug delivery system and preparation method thereof	2020-12-03
CN-112741837-B	Brain-targeting nano-drug delivery system and preparation method thereof	2020-12-03
CN-112480151-A	Novel fluorescent probe, preparation method thereof and application of novel fluorescent probe in detection of sulfadimidine in honey	2020-11-25
CN-112221539-A	Catalyst for hydrosilylation reaction and preparation method and application thereof	2020-11-17
CN-112457797-A	High-temperature-resistant cyanate ester conductive adhesive and preparation method thereof	2020-10-27

Literatures

PMID	Publication Date	Title	Journal
22709587	2012-08-20	Hyaluronic acid-ceramide-based optical/MR dual imaging nanoprobe for cancer diagnosis	Journal of controlled release : official journal of the Controlled Release Society
21922111	2011-12-01	Stability assessment of different chelating moieties used for elemental labeling of bio-molecules	Metallomics : integrated biometal science
20592929	2010-07-01	Visualization of tumor angiogenesis using MR imaging contrast agent Gd-DTPA-anti-VEGF receptor 2 antibody conjugate in a mouse tumor model	Korean journal of radiology
19919931	2009-12-01	Development of a radiolabeled beta-human chorionic gonadotropin	Acta pharmaceutica (Zagreb, Croatia)
17785729	2007-09-01	Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer	Journal of nuclear medicine : official publication, Society of Nuclear Medicine
16102904	2005-10-10	Synthesis and characterization of a novel DTPA polymerized hemoglobin based oxygen carrier	Biochimica et biophysica acta
12433040	2002-11-01	Labeling of monoclonal antibodies with 153Sm for potential use in radioimmunotherapy	Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
10628656	1999-12-01	Charge modification of plasma and milk proteins results in antiviral active compounds	Journal of peptide science : an official publication of the European Peptide Society

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