N-[(3-dimethylamino)-propyl] methacrylamide (DMAPAA)
Product Information
Molecular Formula
C8H16N2O
Molecular Weight
156.22544
Description
DMAPAA is a biomedical compound that characterized by its chemical nomenclature N-[(3-dimethylamino)-propyl] methacrylamide. It holds immense promise for its proficient utilization in the realm of pharmaceutical conveyance platforms. The distinct attributes of DMAPAA furnish an exquisite avenue for targeted therapeutics, thereby augmenting their efficiency and ameliorating the undesired repercussions of medication.
Synonyms
3845-76-9;N-(3-(Dimethylamino)propyl)acrylamide;N,N-Dimethylaminopropylacrylamide;N-[3-(Dimethylamino)propyl]acrylamide;N-(3-Dimethylaminopropyl)acrylamide;N-[3-(dimethylamino)propyl]prop-2-enamide
IUPAC Name
N-[3-(dimethylamino)propyl]prop-2-enamide
SMILES
CN(C)CCCNC(=O)C=C
InChI
InChI=1S/C8H16N2O/c1-4-8(11)9-6-5-7-10(2)3/h4H,1,5-7H2,2-3H3,(H,9,11)
InChI Key
ADTJPOBHAXXXFS-UHFFFAOYSA-N
Boiling Point
142 °C/12 mmHg
Flash Point
140 °C
Purity
95%
Appearance
Colorless to Light orange to Yellow clear liquid
Storage
0-10°C
Refractive Index
n20/D 1.482
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Computed Properties
XLogP3
0.5
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
5
Exact Mass
156.126263138 g/mol
Monoisotopic Mass
156.126263138 g/mol
Topological Polar Surface Area
32.3Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
132
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114014986-A | Highly elastic photosensitive resin composition | 2021-12-09 |
| CN-113990176-A | Preparation method and application of anti-counterfeit label based on temperature-induced phase-change hydrogel | 2021-11-19 |
| CN-113831482-A | CO based on tertiary amine group2Responsive tackifying polymer and preparation method and application thereof | 2021-10-20 |
| CN-113943596-A | Viscosity index improver and preparation method and application thereof | 2021-10-19 |
| CN-113789025-A | Xerogel for removing organic solvent micro-water and preparation method and application thereof | 2021-09-30 |
| CN-113651928-A | Oil-soluble thick oil viscosity reducer and preparation method and application thereof | 2021-08-16 |
| CN-113583645-A | Hydrate inhibitor and application thereof | 2021-06-30 |
| CN-113354333-A | Hyperbranched water-reducing viscosity-reducing concrete admixture and preparation method and application thereof | 2021-05-10 |
| CN-112979882-A | Rust-conversion type high-dispersion polycarboxylate superplasticizer and preparation method thereof | 2021-02-20 |
| CN-112939871-A | Nanometer thermometer based on saturated fatty acid and double-response fluorescent molecule | 2021-01-27 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 20627667 | 2010-09-01 | Direct spectroscopic observation of binding of sugars to polymers having phenylboronic acids substituted with an ortho-phenylazo group | Colloids and surfaces. B, Biointerfaces |
| 21073421 | 2010-08-01 | A new acylamidase from Rhodococcus erythropolis TA37 can hydrolyze N-substituted amides | Biochemistry. Biokhimiia |
| 19899789 | 2009-12-01 | Impact of molecular weight in four-branched star vectors with narrow molecular weight distribution on gene delivery efficiency | Bioconjugate chemistry |
| 19323502 | 2009-05-01 | Determination of glucose levels using a functionalized hydrogel-optical fiber biosensor: toward continuous monitoring of blood glucose in vivo | Analytical chemistry |
| 19062267 | 2009-03-15 | Glucose sensors based on a responsive gel incorporated as a Fabry-Perot cavity on a fiber-optic readout platform | Biosensors & bioelectronics |
| 18491924 | 2008-07-01 | Determination of swelling of responsive gels with nanometer resolution. Fiber-optic based platform for hydrogels as signal transducers | Analytical chemistry |
| 18205325 | 2008-02-01 | Enhancement of star vector-based gene delivery to endothelial cells by addition of RGD-peptide | Bioconjugate chemistry |
| 17881077 | 2007-11-20 | Deposition transfection technology using a DNA complex with a thermoresponsive cationic star polymer | Journal of controlled release : official journal of the Controlled Release Society |
| 17922548 | 2007-11-01 | Synthesis and in vitro evaluation of novel star-shaped block copolymers (blocked star vectors) for efficient gene delivery | Bioconjugate chemistry |
| 17571905 | 2007-07-17 | Heparin bioconjugate with a thermoresponsive cationic branched polymer: a novel aqueous antithrombogenic coating material | Langmuir : the ACS journal of surfaces and colloids |
