GPhos Pd G6

C47H70BrO4PPdSi

944.44

GPhos Pd G6 is a well-defined Buchwald sixth-generation palladacycle precatalyst featuring a GPhos ligand and a 4-((2-(trimethylsilyl)ethoxy)carbonyl)benzen-1-ide palladacycle core with a bromide counterion. It is a powerful precatalyst for classic cross-coupling reactions such as Suzuki-Miyaura, Buchwald-Hartwig amination, and C-N bond formation. The compound is bench-stable and soluble in most organic solvents. This precatalyst offers excellent functional group tolerance and high catalytic activity, making it a valuable tool in pharmaceutical synthesis and organic chemistry research.

Bromo[Dicyclohexyl[3-(1,1-dimethylethoxy)-6-methoxy-2',6'-bis(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine](4-((2-(trimethylsilyl)ethoxy)carbonyl)benzen-1-ide)palladium(II); (SP-4-2)-Bromo[dicyclohexyl[3-(1,1-dimethylethoxy)-6-methoxy-2',6'-bis(1-methylethyl)[1,1'-biphenyl]-2-yl-κC1']phosphine-κP][4-[[2-(trimethylsilyl)ethoxy]carbonyl]phenyl]palladium; Palladium, bromo[dicyclohexyl[3-(1,1-dimethylethoxy)-6-methoxy-2',6'-bis(1-methylethyl)[1,1'-biphenyl]-2-yl-κC1']phosphine-κP][4-[[2-(trimethylsilyl)ethoxy]carbonyl]phenyl]-, (SP-4-2)-; [2-(Dicyclohexylphosphino)-3-tert-butoxy-6-methoxy-2',6'-diisopropyl-1,1'-biphenyl](4-((2-(trimethylsilyl)ethoxy)carbonyl)phenyl-1-yl)palladium bromide

dicyclohexyl-[2-[2,6-di(propan-2-yl)phenyl]-3-methoxy-6-[(2-methylpropan-2-yl)oxy]phenyl]phosphane;palladium(2+);2-trimethylsilylethyl benzoate;bromide

CC(C)C1=C(C(=CC=C1)C(C)C)C2=C(C=CC(=C2P(C3CCCCC3)C4CCCCC4)OC(C)(C)C)OC.C[Si](C)(C)CCOC(=O)C1=CC=[C-]C=C1.[Br-].[Pd+2]

InChI=1S/C35H53O2P.C12H17O2Si.BrH.Pd/c1-24(2)28-20-15-21-29(25(3)4)32(28)33-30(36-8)22-23-31(37-35(5,6)7)34(33)38(26-16-11-9-12-17-26)27-18-13-10-14-19-27;1-15(2,3)10-9-14-12(13)11-7-5-4-6-8-11;;/h15,20-27H,9-14,16-19H2,1-8H3;5-8H,9-10H2,1-3H3;1H;/q;-1;;+2/p-1

ICGQAPULPXXSAB-UHFFFAOYSA-M

98%

Light yellow powder

Store at 2-8 °C, sealed storage, away from moisture