HO-PEG7-OH
Product Information
Molecular Formula
C14H30O8
Molecular Weight
326.38
Description
HO-PEG7-OH is a polyethylene glycol (PEG)-based PROTAC linker that can be used in the synthesis of a series of PROTACs.
Synonyms
Heptaethylene Glycol; 3,6,9,12,15,18-Hexaoxaeicosane-1,20-diol; NSC 97395; 2-{2-[2-(2-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}ethan-1-ol
IUPAC Name
2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
SMILES
C(COCCOCCOCCOCCOCCOCCO)O
InChI
InChI=1S/C14H30O8/c15-1-3-17-5-7-19-9-11-21-13-14-22-12-10-20-8-6-18-4-2-16/h15-16H,1-14H2
InChI Key
XPJRQAIZZQMSCM-UHFFFAOYSA-N
Boiling Point
244°C at 0.6 mmHg
Purity
≥95%
Density
1.13±0.06 g/cm3 (Predicted)
Solubility
Soluble in Chloroform (Sparingly), Ethyl Acetate (Slightly)
Appearance
Colorless to light yellow to light orange clear liquid
Storage
Store at 2-8°C
Refractive Index
1.4653 (589.3 nm 20°C)
LogP
-0.92940
Computed Properties
XLogP3
-2
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
8
Rotatable Bond Count
19
Exact Mass
326.19406791 g/mol
Monoisotopic Mass
326.19406791 g/mol
Topological Polar Surface Area
95.8Ų
Heavy Atom Count
22
Formal Charge
0
Complexity
174
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114027309-A | Iodine-containing disinfectant containing polyvinylpyrrolidone and polyol ether and preparation method thereof | 2021-11-12 |
| CN-113980259-A | Method for preparing polycarbonate by using 1,1,3,3,4,4,6, 6-octamethyltetrahydropentene-2, 5-diol | 2021-10-14 |
| CN-113234117-A | Hederagenin C-28 polyethylene glycol modified derivative and preparation method thereof | 2021-06-24 |
| CN-113527405-A | Application of hederagenin polyethylene glycol modified derivative in preparation of tumor drug resistance reversal agent | 2021-06-24 |
| CN-113248352-A | Method for solid-phase synthesis of heptaethylene glycol monomethyl ether | 2021-05-18 |
| CN-112979937-A | Polycarbonate and synthetic method thereof, rigid monomer and preparation method thereof | 2021-04-26 |
| CN-112979937-B | Polycarbonate and synthetic method thereof, rigid monomer and preparation method thereof | 2021-04-26 |
| CN-112897549-A | Method for regulating and controlling pore size of molecular sieve and application thereof | 2021-02-26 |
| CN-112760740-A | Bio-based 2, 5-furandicarboxylic acid based copolyester fiber and preparation method and application thereof | 2021-01-18 |
| WO-2022054813-A1 | Electrochemical device | 2020-09-11 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 16472740 | 2006-02-01 | Complete reaction cycle of a cocaine catalytic antibody at atomic resolution | Structure (London, England : 1993) |
