Melamine
Product Information
Molecular Formula
C3H6N6
Molecular Weight
126.12
Description
Melamine forms synthetic resins with formaldehyde.
Synonyms
Metformin EP Impurity D; Melamine (USP); Cyanuramide; 2,4,6-Triamino-s-triazine; Isomelamine; Theoharn; Triaminotriazine
IUPAC Name
1,3,5-triazine-2,4,6-triamine
SMILES
C1(=NC(=NC(=N1)N)N)N
InChI
InChI=1S/C3H6N6/c4-1-7-2(5)9-3(6)8-1/h(H6,4,5,6,7,8,9)
InChI Key
JDSHMPZPIAZGSV-UHFFFAOYSA-N
Boiling Point
299.696 °C at 760 mmHg
Melting Point
>300 °C (sublimes)
Flash Point
135.052°C
Purity
> 98 %
Density
1.573 g/cm3
Solubility
Soluble in DMSO (Slightly, Heated)
Appearance
White Solid
Application
Forms synthetic resins with formaldehyde.
Storage
Keep in dark place, Inert atmosphere, Room temperature
Refractive Index
1.922
Stability
Stable. Incompatible with strong acids, strong oxidizing agents. Nonflammable.
LogP
0.36180
Vapor Pressure
0.001mmHg at 25°C
Decomposition
Dangerous; when heated to decomp, Emits highly toxic fumes of /nitrogen oxides and hydrogen cyanide
Safety Information
Hazards
H361
Precautionary Statement
P201, P202, P281, P308+P313, P405, and P501
GHS Pictogram
GHS08
Signal Word
Warning
Computed Properties
XLogP3
-1.4
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
0
Exact Mass
126.06539422
Monoisotopic Mass
126.06539422
Topological Polar Surface Area
117
Heavy Atom Count
9
Formal Charge
0
Complexity
63.3
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022024876-A1 | Colored resin composition, color filter, image display device, and colorant dispersion | 2020-07-31 |
| WO-2021190569-A1 | Low-migration hindered phenol antioxidant compound, preparation method and composition | 2020-03-26 |
| US-2021293169-A1 | Combined Catalyst Precursor/Surfactant Mixture For Reductant Urea Solution For Selective Catalytic Reduction | 2020-03-20 |
| US-11391190-B2 | Combined catalyst precursor/surfactant mixture for reductant urea solution for selective catalytic reduction | 2020-03-20 |
| KR-102331896-B1 | Flame retardant microcapsule and preparation method thereof | 2020-01-21 |
| US-11286327-B2 | FR composite composition for light-based additive manufacturing | 2019-12-05 |
| WO-2020045467-A1 | Resin composition, pellet, composite molded body, method for producing composite molded body, and tank | 2018-08-29 |
| CN-108530369-A | A kind of synthetic method of 1,3,5- triazines -2,4,6- triamines | 2018-04-25 |
| CN-108559047-A | A kind of preparation method of flame retardant polyurethane interpenetrating net polymer | 2018-01-27 |
| WO-2018167507-A1 | Porous boron nitride | 2017-03-17 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 34842327 | 2022-03-01 | Melamine induced changes in histopathology of the main organs and transcriptional levels of MAPK signaling genes in kidneys of female mice | Environmental toxicology |
| 33211169 | 2021-02-01 | Expression of stem cell markers as useful complementary factors in the early detection of urinary bladder carcinogens by immunohistochemistry for γ-H2AX | Archives of toxicology |
| 32113805 | 2020-06-15 | Activities of metabolizing enzymes in human placenta | Toxicology letters |
| 30055240 | 2018-10-15 | Melamine causes testicular toxicity by destroying blood-testis barrier in piglets | Toxicology letters |
| 28206646 | 2018-06-01 | Acute Melamine Affects Spatial Memory Consolidation via Inhibiting Hippocampal NMDAR-Dependent LTD in Rats | Toxicological sciences : an official journal of the Society of Toxicology |
| 24273086 | 2014-03-01 | Use of an avian hepatocyte assay and the avian Toxchip Polymerse chain reaction array for testing prioritization of 16 organic flame retardants | Environmental toxicology and chemistry |
| 23052191 | 2013-03-01 | Repeat oral dose toxicity studies of melamine in rats and monkeys | Archives of toxicology |
| 23022069 | 2013-01-01 | Performance of urinary and gene expression biomarkers in detecting the nephrotoxic effects of melamine and cyanuric acid following diverse scenarios of co-exposure | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association |
| 22980858 | 2012-12-15 | Monoclonal antibody based inhibition ELISA as a new tool for the analysis of melamine in milk and pet food samples | Food chemistry |
| 22953938 | 2012-12-01 | Sensitive fluorescent detection of melamine in raw milk based on the inner filter effect of Au nanoparticles on the fluorescence of CdTe quantum dots | Food chemistry |
