Methyl 2-Fluoroacrylate
Product Information
Molecular Formula
C4H5FO2
Molecular Weight
104.08
Description
Methyl 2-Fluoroacrylate is a pivotal chemical constituent dominant in the biomedicine arena. It assumes a vital role in the manufacturing of pharmacological remedies specifically engineered to combat the enigmatic complexities of ailments, notably cancer and viral afflictions. This exceptionally versatile compound serves as a fundamental cornerstone in the innovative formulation of therapeutic interventions endowed with prodigious antineoplastic and antiviral attributes.
Synonyms
2-Fluoroacrylic Acid Methyl Ester (stabilized with BHT)
IUPAC Name
methyl 2-fluoroprop-2-enoate
SMILES
COC(=O)C(=C)F
InChI
InChI=1S/C4H5FO2/c1-3(5)4(6)7-2/h1H2,2H3
InChI Key
ZTZJVAOTIOAZGZ-UHFFFAOYSA-N
Boiling Point
91 °C
Flash Point
1 °C
Purity
>98.0%(GC)
Density
1.057g/cm3
Appearance
Colorless to Almost colorless clear liquid
Storage
0-10°C
Refractive Index
1.39
Safety Information
Hazards
H225:
Highly flammable liquid and vapour.
H301:
Toxic if swallowed.
H372:
Causes damage to organs through prolonged or repeated exposure.
H411:
Toxic to aquatic life with long-lasting effects.
Highly flammable liquid and vapour.
H301:
Toxic if swallowed.
H372:
Causes damage to organs through prolonged or repeated exposure.
H411:
Toxic to aquatic life with long-lasting effects.
Precautionary Statement
P210:
Keep away from heat, sparks, open flames, hot surfaces. No smoking.
P260:
Do not breathe dust, fumes, gas, mist, vapours, spray.
P273:
Avoid release to the environment.
P301+P310+P330:
IF SWALLOWED:
Immediately call a POISON CENTER or doctor/physician.
Rinse mouth.
P370+P378:
In case of fire:
Use for extinction:
P391:
Collect spillage.
Keep away from heat, sparks, open flames, hot surfaces. No smoking.
P260:
Do not breathe dust, fumes, gas, mist, vapours, spray.
P273:
Avoid release to the environment.
P301+P310+P330:
IF SWALLOWED:
Immediately call a POISON CENTER or doctor/physician.
Rinse mouth.
P370+P378:
In case of fire:
Use for extinction:
P391:
Collect spillage.
Computed Properties
XLogP3
1
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
2
Exact Mass
104.02735756 g/mol
Monoisotopic Mass
104.02735756 g/mol
Topological Polar Surface Area
26.3Ų
Heavy Atom Count
7
Formal Charge
0
Complexity
97.9
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114015335-A | Environment-friendly waterproof coating and preparation method thereof | 2021-11-09 |
| CN-113427937-A | Transfer printing paper and preparation method thereof | 2021-07-14 |
| CN-113427937-B | Transfer printing paper and preparation method thereof | 2021-07-14 |
| CN-113480429-A | Synthetic method of alpha-fluoroacrylate | 2021-06-29 |
| CN-112745617-A | Heat insulation type acrylic plate | 2020-12-28 |
| WO-2022054894-A1 | Production method of acrylic acid derivative | 2020-09-11 |
| WO-2022049376-A1 | Novel compounds | 2020-09-01 |
| CN-111876103-A | Bi-component AB adhesive applicable to liquid oxygen environment | 2020-08-20 |
| JP-2022042483-A | Acrylic acid ester compound purification method | 2020-08-19 |
| WO-2022039241-A1 | Method for purifying acrylic acid ester compound | 2020-08-19 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 19904924 | 2009-12-17 | 4-Fluoro-2,4-methanoproline | Organic letters |
