METHYLZINC CHLORIDE
Product Information
Molecular Formula
CH3ClZn
Molecular Weight
115.88
Description
Methylzinc chloride can be used in: • Ni-catalyzed one-pot Negishi coupling with amino-heteroaryl chlorides.• Cross-coupling with aryl fluorides in the presence of a nickel catalyst.
Synonyms
Methylzinc chloride
IUPAC Name
carbanidechlorozinc(1+)
SMILES
[CH3-].Cl[Zn+]
InChI
InChI=1S/CH3.ClH.Zn/h1H31H/q-1+2/p-1
InChI Key
NMLXKNNXODLJIN-UHFFFAOYSA-M
Boiling Point
67 °C
Flash Point
1.4 °F - closed cup
Density
1.033
Safety Information
Hazards
H225 - H302 - H314 - H335 - H351
Precautionary Statement
P210 - P260 - P280 - P305 + P351 + P338 - P370 + P378 - P403 + P235
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
0
Exact Mass
113.921470 g/mol
Monoisotopic Mass
113.921470 g/mol
Topological Polar Surface Area
0Ų
Heavy Atom Count
3
Formal Charge
0
Complexity
4.8
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022006543-A1 | 5-[5-(piperidin-4-yl)thieno[3,2-c]pyrazol-2-yl]indazole derivatives and related compounds as modulators for splicing nucleic acids and for the treatment of proliferative diseases | 2020-07-02 |
| WO-2020216764-A1 | Modulators of the integrated stress response pathway | 2019-04-23 |
| AU-2020262153-A1 | Modulators of the integrated stress response pathway | 2019-04-23 |
| CA-3137212-A1 | Modulators of the integrated stress response pathway | 2019-04-23 |
| EP-3959210-A1 | Modulators of the integrated stress response pathway | 2019-04-23 |
| JP-2018100270-A | Pharmaceutical comprising 1,4-disubstituted imidazole derivative | 2016-12-20 |
| JP-6775483-B2 | Pharmaceuticals consisting of 1,4-di-substituted imidazole derivatives | 2016-12-20 |
| AU-2016284398-A1 | 1,4-di-substituted imidazole derivative | 2015-06-22 |
| CA-2990583-A1 | 1,4-disubstituted imidazole derivative | 2015-06-22 |
| EP-3312170-A1 | 1,4-di-substituted imidazole derivative | 2015-06-22 |
