N-Boc-1,2,3,6-tetrahydropyridine-4-boronic Acid Pinacol Ester
| Catalog Number | Size | Price | Stock | Quantity |
|---|---|---|---|---|
| BPM-312055 | 100 g | $398 | In stock |
Product Information
Molecular Formula
C16H28NO4B
Molecular Weight
309.21
Description
Reagent used for : Suzuki-Miyaura cross-coupling using palladium phosphine catalyst ; Palladium-catalyzed ligand-controlled regioselective Suzuki coupling ; Palladium-catalyzed Suzuki-Miyaura coupling ; Suzuki coupling followed by iodolactonization reaction ; Wrenchnolol derivative optimized for gene activation in cells Reagent used in Preparation of several enzymatic inhibitors and receptor ligands; Orally active anaplastic lymphoma kinase inhibitors ; Oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes ; 4-arylpiperidinyl amides and N-arylpiperidin-3-yl-cyclopropanecarboxamides as novel melatonin receptor ligands ; Quinazoline analogs as glucocerebrosidase inhibitors with chaperone activity for treatment of Gaucher disease, a lysosomal storage disorder ; Arylpiperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists.
Synonyms
4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylate
IUPAC Name
tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylate
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CCN(CC2)C(=O)OC(C)(C)C
InChI
InChI=1S/C16H28BNO4/c1-14(2,3)20-13(19)18-10-8-12(9-11-18)17-21-15(4,5)16(6,7)22-17/h8H,9-11H2,1-7H3
InChI Key
VVDCRJGWILREQH-UHFFFAOYSA-N
Boiling Point
348 °C at 760 mmHg
Melting Point
100-114 °C
Flash Point
Not applicable
Purity
95 %
Density
1.05 g/cm3
LogP
3.12290
Safety Information
Precautionary Statement
P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362
Signal Word
Warning
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
3
Exact Mass
309.2111385 g/mol
Monoisotopic Mass
309.2111385 g/mol
Topological Polar Surface Area
48Ų
Heavy Atom Count
22
Formal Charge
0
Complexity
463
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113480534-A | Benzimidazole or azabenzimidazole-6-carboxylic acid compounds and application thereof | 2021-07-23 |
| CN-113304151-A | Application of nitrofuran small-molecular compound in preparation of drug for inducing iron death and/or slowing down chemotherapy drug resistance of gastric cancer | 2021-04-15 |
| CN-113620943-A | Nitrofuran compound, pharmaceutical composition, preparation method and application thereof | 2021-04-15 |
| CN-112778294-A | 5-aminoisoxazole derivative and application thereof in preparation of multi-kinase inhibitor | 2021-01-07 |
| CN-113321645-A | 5-aminoisoxazole derivative and application thereof in preparation of multi-kinase inhibitor | 2021-01-07 |
| CN-114181205-A | Pyrazolopyridine compound or salt thereof, and preparation method and application thereof | 2020-09-14 |
| CN-114163444-A | Chimeric compound for targeted degradation of androgen receptor protein, preparation method thereof and application thereof in medicine | 2020-09-11 |
| WO-2022051568-A1 | Substituted 4-piperidinyl-pyrrolo[2,3-b]pyridines and related compounds and their use in treating medical conditions | 2020-09-04 |
| WO-2022049496-A1 | Novel compounds as histone deacetylase 6 inhibitor, and pharmaceutical composition comprising the same | 2020-09-02 |
| WO-2022042691-A1 | Heterocyclic glp-1 agonists | 2020-08-28 |
