Nickel(II) chloride hydrate
Product Information
Molecular Formula
NiCl2 · xH2O
Molecular Weight
129.60 (anhydrous basis)
Description
Nickel(II) chloride hydrate is an esteemed chemical compound prevalent in the biomedical sphere and plays a pivotal catalytic function within diverse biological reactions. Remarkably, it boasts multifaceted prowess, encompassing the treatment of specific ailments like cancer and its indispensable role as a reagent in drug synthesis.
Synonyms
Nickel dichloride hydrate
IUPAC Name
dichloronickelhydrate
SMILES
O.Cl[Ni]Cl
InChI
InChI=1S/2ClH.Ni.H2O/h2*1H1H2/q+2/p-2
InChI Key
HGGYAQHDNDUIIQ-UHFFFAOYSA-L
Purity
99.95% trace metals basis
Safety Information
Hazards
H301 + H331 - H315 - H317 - H334 - H350i - H360D - H372 - H410
Precautionary Statement
P201 - P273 - P280 - P301 + P310 + P330 - P302 + P352 - P304 + P340 + P311
Computed Properties
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
0
Exact Mass
145.883612 g/mol
Monoisotopic Mass
145.883612 g/mol
Topological Polar Surface Area
1Ų
Heavy Atom Count
4
Formal Charge
0
Complexity
2.8
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113955814-A | NiCl synthesized at low temperature2Powder and use | 2021-11-30 |
| CN-113831535-A | Preparation method of polyarylethersulfone resin, polyarylethersulfone resin obtained by preparation method and application of polyarylethersulfone resin | 2021-09-29 |
| CN-113913016-A | Polyarylethersulfone composition and preparation method and application thereof | 2021-09-29 |
| CN-113457740-A | Catalyst for preparing ethanol by catalytic hydrogenation of methyl acetate and preparation method thereof | 2021-05-31 |
| CN-113445087-A | Preparation method of environment-friendly high-strength corrosion-resistant aluminum alloy | 2021-05-13 |
| CN-112375082-A | Series of carbazole derivatives and application thereof | 2020-11-23 |
| CN-112521343-A | Organic electroluminescent material and device thereof | 2020-11-23 |
| CN-112086289-A | Sunlight-driven electricity-oxygen co-production seawater battery and preparation method thereof | 2020-08-12 |
| KR-20200080212-A | Light-emitting device comprising perovskite-organic small molecule-mixed light-emitting layer and preparation method thereof | 2020-06-26 |
| KR-102285319-B1 | Catalysts for hydrogen evolution reaction including rhodium-nickel alloy nanofibers and method of preparing rhodium-nickel alloy nanofibers | 2019-12-17 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 34571076 | 2021-11-01 | Nickel chloride regulates ANGPTL4 via the HIF-1α-mediated TET1 expression in lung cells | Toxicology letters |
| 33596451 | 2021-04-15 | Lactate released from human fibroblasts enhances Ni elution from Ni plate | Toxicology |
| 30724446 | 2019-05-01 | Nickel-induced VEGF expression via regulation of Akt, ERK1/2, NFκB, and AMPK pathways in H460 cells | Environmental toxicology |
| 29355601 | 2018-02-15 | Nickel ions bind to HSP90β and enhance HIF-1α-mediated IL-8 expression | Toxicology |
| 26004978 | 2015-08-06 | Further development of the theory and mathematical description of combined toxicity: An approach to classifying types of action of three-factorial combinations (a case study of manganese-chromium-nickel subchronic intoxication) | Toxicology |
| 24158569 | 2014-04-01 | Nickel induces interleukin-1β secretion via the NLRP3-ASC-caspase-1 pathway | Inflammation |
| 24448832 | 2014-04-01 | Nickel-induced cell death and survival pathways in cultured renal proximal tubule cells: roles of reactive oxygen species, ceramide and ABCB1 | Archives of toxicology |
| 24612858 | 2014-03-10 | Whole adult organism transcriptional profiling of acute metal exposures in male zebrafish | BMC pharmacology & toxicology |
| 24577088 | 2014-02-27 | MiRNA-210 modulates a nickel-induced cellular energy metabolism shift by repressing the iron-sulfur cluster assembly proteins ISCU1/2 in Neuro-2a cells | Cell death & disease |
| 23792913 | 2013-09-01 | Synthesis, structure and antifungal activity of thiophene-2,3-dicarboxaldehyde bis(thiosemicarbazone) and nickel(II), copper(II) and cadmium(II) complexes: unsymmetrical coordination mode of nickel complex | Journal of inorganic biochemistry |
