Norbornene epoxide
Product Information
Molecular Formula
C7H10O
Molecular Weight
110.1537
Description
Norbornene epoxide is a versatile compound widely used in the biomedical industry. It is commonly employed in the synthesis of various pharmaceuticals and biologically active compounds. Known for its reactivity and stability, Norbornene epoxide serves as a valuable intermediate in the production of drugs targeting diseases ranging from cancer to neurological disorders.
Synonyms
3-oxatricyclo[3.2.1.02,4]octane; NORBORNENE EPOXIDE; 2,3-Epoxybicyclo[2.2.1]heptane; 2,3-Epoxynorbornane; 2,5-Methano-7-oxabicyclo[4.1.0]heptane; Einecs 205-995-7
IUPAC Name
3-oxatricyclo[3.2.1.02,4]octane
SMILES
C1CC2CC1C3C2O3
InChI
InChI=1S/C7H10O/c1-2-5-3-4(1)6-7(5)8-6/h4-7H,1-3H2
InChI Key
OHNNZOOGWXZCPZ-UHFFFAOYSA-N
Boiling Point
170.2°C at 760mmHg
Melting Point
126°C
Flash Point
10.0±0.0°C
Purity
95%
Density
1.159g/cm3
Appearance
White to Almost white powder to crystal
Safety Information
Hazards
H228:
Flammable solid.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Flammable solid.
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P210:
Keep away from heat, sparks, open flames, hot surfaces. No smoking.
P240:
Ground/bond container and receiving equipment.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P370+P378:
In case of fire:
Use for extinction:
Keep away from heat, sparks, open flames, hot surfaces. No smoking.
P240:
Ground/bond container and receiving equipment.
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P370+P378:
In case of fire:
Use for extinction:
Computed Properties
XLogP3
1.1
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
0
Exact Mass
110.073164938 g/mol
Monoisotopic Mass
110.073164938 g/mol
Topological Polar Surface Area
12.5Ų
Heavy Atom Count
8
Formal Charge
0
Complexity
118
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
4
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| JP-6924888-B1 | Refrigeration cycle equipment | 2020-12-04 |
| WO-2022056053-A1 | Polypropylene polymer having ultra-high melt flow rate | 2020-09-09 |
| JP-2022014019-A | Polycarbonate resin composition | 2020-07-06 |
| JP-2021188010-A | Polycarbonate resin composition | 2020-06-03 |
| JP-2021188011-A | Polycarbonate resin composition | 2020-06-03 |
| JP-6821075-B1 | Refrigeration cycle equipment | 2020-04-22 |
| CN-113531931-A | Refrigeration cycle device | 2020-04-22 |
| JP-2021173454-A | Refrigeration cycle equipment | 2020-04-22 |
| KR-102178342-B1 | A lateral heterojunction sheet and manufacturing method thereof | 2020-04-10 |
| KR-102151214-B1 | A multi layer sheet manufacturing plastic foam and plastic form using thereof | 2020-03-27 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21126137 | 2010-01-01 | Early gynaecological assessment following Stevens-Johnson syndrome/toxic epidermal necrolysis | Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology |
| 12059232 | 2002-06-19 | Solution and solid-state structural studies of epoxide adducts of cadmium phenoxides. Chemistry relevant to epoxide activation for ring-opening reactions | Journal of the American Chemical Society |
| 11836122 | 2002-04-01 | New 2,N6-disubstituted adenosines: potent and selective A1 adenosine receptor agonists | Bioorganic & medicinal chemistry |
