Oseltamivir EP Impurity H
Product Information
Molecular Formula
C12H27OP
Molecular Weight
218.32
Description
Oseltamivir EP Impurity H is an impurity of Oseltamivir which can be used in COVID19-related research.
Synonyms
Tri-n-butylphosphine oxide; Trisbutylphosphine oxide; Tributylfosfinoxid
IUPAC Name
1-dibutylphosphorylbutane
SMILES
CCCCP(=O)(CCCC)CCCC
InChI
InChI=1S/C12H27OP/c1-4-7-10-14(13,11-8-5-2)12-9-6-3/h4-12H2,1-3H3
InChI Key
MNZAKDODWSQONA-UHFFFAOYSA-N
Boiling Point
150 °C/1.5 mmHg (lit.)
Melting Point
64-69 °C (lit.)
Flash Point
Not applicable
Purity
99.99%
Density
0.8480 g/cm3
Solubility
Soluble in Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Sparingly)
Appearance
Off-White Semi-Solid to Solid
Application
Oseltamivir (O701000) impurity.
Storage
Store at 2-8°C
Safety Information
Hazards
H302 + H312 + H332 - H314
Precautionary Statement
P280 - P305 + P351 + P338 - P310
Computed Properties
XLogP3
3.1
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
9
Exact Mass
218.179952478 g/mol
Monoisotopic Mass
218.179952478 g/mol
Topological Polar Surface Area
17.1Ų
Heavy Atom Count
14
Formal Charge
0
Complexity
137
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113845656-A | Composition for preparing glass-like body, glass-like body and preparation method and application thereof | 2021-11-08 |
| CN-113979476-A | Method for preparing ammonium tetramolybdate product by back extraction and impurity removal | 2021-10-26 |
| CN-113991045-A | Pure blue light perovskite luminescent layer, preparation method thereof and light emitting diode | 2021-10-11 |
| CN-113820923-A | Direct photo-patterning method of nano-crystal film without cross-linking agent and photoresist | 2021-09-16 |
| CN-113697888-A | Extracting agent and method for treating phenol-ammonia wastewater | 2021-09-01 |
| CN-113698931-A | Nanocrystalline/alumina core-shell structure luminescent material and preparation method thereof | 2021-08-30 |
| CN-113322070-A | CdS/CdSe heterojunction quantum dot with core/shell structure and preparation method thereof | 2021-07-01 |
| CN-113322070-B | CdS/CdSe heterojunction quantum dot with core/shell structure and preparation method thereof | 2021-07-01 |
| CN-113241501-A | Preparation method of flame-retardant and easily-carbonized lithium ion battery diaphragm | 2021-05-10 |
| CN-113105885-A | Perovskite/zinc oxide heterostructure luminescent material and preparation method thereof | 2021-04-15 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 26530989 | 2016-01-01 | Pyrethroid resistance in Phytoseiulus macropilis (Acari: Phytoseiidae): cross-resistance, stability and effect of synergists | Experimental & applied acarology |
| 24738222 | 2014-01-01 | [Pyrethroid resistance mechanisms in the body lice Pediculus humanus humanus L.: detoxification enzyme systems] | Meditsinskaia parazitologiia i parazitarnye bolezni |
| 21656898 | 2011-12-01 | Esterase inhibition by synergists in the western flower thrips Frankliniella occidentalis | Pest management science |
| 21946931 | 2011-11-07 | Molecular recognition probes of solvation thermodynamics in solvent mixtures | Organic & biomolecular chemistry |
| 21882703 | 2011-08-01 | Cross-resistance to insecticides in a malathion-resistant strain of Ceratitis capitata (Diptera: Tephritidae) | Journal of economic entomology |
| 21308959 | 2011-03-01 | Characterisation of spinosad resistance in the housefly Musca domestica (Diptera: Muscidae) | Pest management science |
| 20853424 | 2010-11-01 | Effects of functionalized fullerenes on bifenthrin and tribufos toxicity to Daphnia magna: Survival, reproduction, and growth rate | Environmental toxicology and chemistry |
| 20609220 | 2010-07-07 | Biochemical basis of permethrin resistance in Anopheles arabiensis from Lower Moshi, north-eastern Tanzania | Malaria journal |
| 20449502 | 2010-04-21 | A thermodynamic study of selective solvation in solvent mixtures | Organic & biomolecular chemistry |
| 20429463 | 2010-04-01 | Insecticide resistance profiles and synergism in field populations of the German cockroach (Dictyoptera: Blattellidae) from Singapore | Journal of economic entomology |
