Poly(N-isopropyl acrylamide)

Product Information

Molecular Formula:
C6H11NO
Molecular Weight:
113.15800
Description
Polymer is water-soluble at room temperature. insoluble above ~40º. Solubility ceiling has been used in mold and cell growth techniques since cells adhere to polymer film at incubation temperatures and are released as medium is cooled and polymer is dissolved.
Synonyms: PNIPAM; Poly(N-isopropylacrylamide); PolyNIPAAm; NIPAM polymer
Synonyms
N-ISOPROPYLACRYLAMIDE; Nipam; N-Iso-Propylacrylamide; N-Isopropyl acrylamide; 2-Propenamide, N-(1-methylethyl)-; N-propan-2-ylprop-2-enamide; Isopropyl acrylamide; Acrylamide, N-isopropyl-; N-(1-Methylethyl)-2-propenamide; 25189-55-3; Isopropylamid kyseliny akrylove; N-(propan-2-yl)prop-2-enamide; N-sopropylacrylamde; N-Isopropylacrylamide, (stabilized with MEHQ)
IUPAC Name
N-propan-2-ylprop-2-enamide
Canonical SMILES
CC(C)NC(=O)C=C
InChI
InChI=1S/C6H11NO/c1-4-6(8)7-5(2)3/h4-5H,1H2,2-3H3,(H,7,8)
InChI Key
QNILTEGFHQSKFF-UHFFFAOYSA-N
Melting Point
>200°
Purity
95%
Solubility
In water, 3.077X10+4 mg/L at 25 °C (est)
Appearance
Crystalline solid
Application
Used in binders for textiles, paper, adhesives, detergents, and cosmetics.
Storage
Store at room temperature
Tg
85°
Stability
Stable under recommended storage conditions.
LogP
log Kow = 0.57 (est)
Vapor Pressure
0.02 [mmHg]
Henry's Law Constant
2.28X10-8 atm-cu m/mol at 25 °C (est)
Decomposition
Hazardous decomposition products /formed under fire conditions/: Carbon oxides, nitrogen oxides (NOx)

Safety Information

Hazards
Harmless-use normal precautions
Handling
Exercise normal care

Computed Properties

XLogP3
0.9
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
2
Exact Mass
113.084063974 g/mol
Monoisotopic Mass
113.084063974 g/mol
Topological Polar Surface Area
29.1Ų
Heavy Atom Count
8
Formal Charge
0
Complexity
96.7
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114031329-A Concrete repair material, concrete repair coating and preparation method thereof 2022-01-11
CN-114015012-A High polymer grouting material for pavement construction and preparation method thereof 2022-01-06
JP-2022031470-A Method for producing sheet-shaped cell culture 2021-12-27
CN-114149571-A Imidazole ionic liquid catalyzed vinyl monomer and cyclic ester monomer hybrid polymerization method 2021-12-23
CN-113999476-A Dual-stimulus-responsive conductive composite hydrogel and preparation method and application thereof 2021-12-21
CN-114015080-A Preparation method and application of inorganic/organic composite hydrogel driver 2021-12-21
CN-114133486-A Bionic anisotropic hybrid cross-linked hydrogel and preparation method and application thereof 2021-12-21
CN-114163664-A Preparation method and application of universal double-layer hydrogel driver 2021-12-21
CN-114053488-A Durable lubricating coating on surface of medical catheter and preparation method thereof 2021-12-17
CN-114105703-A Slow-release antibacterial amino acid water-soluble fertilizer and preparation method thereof 2021-12-17

Literatures

PMID Publication Date Title Journal
28930445 2017-11-13 Thermoresponsive and Active Functional Fiber Mats for Cultured Cell Recovery Biomacromolecules
22589075 2012-12-01 ARGET-ATRP synthesis and characterization of PNIPAAm brushes for quantitative cell detachment studies Biointerphases
22939253 2012-12-01 Effect of grafting architecture on the surfactant-like behavior of clay-poly(NiPAAm) nanohybrids Journal of colloid and interface science
23109107 2012-12-01 How to control the recombinant prion protein adhesion for successful storage through modification of surface properties Biointerphases
22915556 2012-11-14 Shell cross-linking of cyclodextrin-based micelles via supramolecular chemistry for the delivery of drugs Macromolecular rapid communications
22019050 2012-11-01 Self-oscillating surface of gel for autonomous mass transport Colloids and surfaces. B, Biointerfaces
22143027 2012-11-01 Modulation of graft architectures for enhancing hydrophobic interaction of biomolecules with thermoresponsive polymer-grafted surfaces Colloids and surfaces. B, Biointerfaces
22813847 2012-11-01 Thermally responsive microcarriers with optimal poly(N-isopropylacrylamide) grafted density for facilitating cell adhesion/detachment in suspension culture Acta biomaterialia
22786875 2012-10-26 Amine-reactive polymers synthesized by RAFT polymerization using an azlactone functional trithiocarbonate RAFT agent Macromolecular rapid communications
23013607 2012-10-24 Surface modification of siliceous materials using maleimidation and various functional polymers synthesized by reversible addition-fragmentation chain transfer polymerization ACS applied materials & interfaces
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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