| Molecular Weight | Description |
|---|---|
| Mw of PCL, PEG, PCL is ~5,000, ~5,000, ~5,000, respectively | Caprolactone itself is a biodegradable polyester with a relatively low melting point (60C) but a glass transition temperature (Tg) around -60C. The high crystallinity in the polyester accounts for this property balance. It is made by metal catalyzed ring opening polymerization of epsilon caprolactone. A typical molecular weight of standard polycaprolactone homopolymer is 188k Daltons. By comparison. a 100% polylactic acid homopolymer with Mw 330k Daltons has a (Tg) temperature of +55C and a melting temperature. Tm of about 175C. Further modifications of polycaprolactone are possible by converting it into diblock (A-B) or triblock (A-B-A) copolymers with polyethylene glycol. Synthetic methods which lead to block structures allow the polymer to have controlled biodegradation rates as well as improved physiological compatibility characteristics. Low molecular weight PEG blocks or caprolactone blocks are tolerated in the human body and are excretable. Such amphiphilic block copolymers are also convertible into polymersomes or vesicles which may contain active compounds (API) which are released during degradation. |
| Mw of PCL, PEG, PCL is ~5,000, ~1,000, ~5,000, respectively | Caprolactone itself is a biodegradable polyester with a relatively low melting point (60C) but a glass transition temperature (Tg) around -60C. The high crystallinity in the polyester accounts for this property balance. It is made by metal catalyzed ring opening polymerization of epsilon caprolactone. A typical molecular weight of standard polycaprolactone homopolymer is 188k Daltons. By comparison. a 100% polylactic acid homopolymer with Mw 330k Daltons has a (Tg) temperature of +55C and a melting temperature. Tm of about 175C. Further modifications of polycaprolactone are possible by converting it into diblock (A-B) or triblock (A-B-A) copolymers with polyethylene glycol. Synthetic methods which lead to block structures allow the polymer to have controlled biodegradation rates as well as improved physiological compatibility characteristics. Low molecular weight PEG blocks or caprolactone blocks are tolerated in the human body and are excretable. Such amphiphilic block copolymers are also convertible into polymersomes or vesicles which may contain active compounds (API) which are released during degradation. |
| Mw of PCL, PEG, PCL is ~1,000, ~10,000, ~1,000, respectively | Caprolactone itself is a biodegradable polyester with a relatively low melting point (60C) but a glass transition temperature (Tg) around -60C. The high crystallinity in the polyester accounts for this property balance. It is made by metal catalyzed ring opening polymerization of epsilon caprolactone. A typical molecular weight of standard polycaprolactone homopolymer is 188k Daltons. By comparison. a 100% polylactic acid homopolymer with Mw 330k Daltons has a (Tg) temperature of +55C and a melting temperature. Tm of about 175C. Further modifications of polycaprolactone are possible by converting it into diblock (A-B) or triblock (A-B-A) copolymers with polyethylene glycol. Synthetic methods which lead to block structures allow the polymer to have controlled biodegradation rates as well as improved physiological compatibility characteristics. Low molecular weight PEG blocks or caprolactone blocks are tolerated in the human body and are excretable. Such amphiphilic block copolymers are also convertible into polymersomes or vesicles which may contain active compounds (API) which are released during degradation. |
| Mw of PCL, PEG, PCL is ~5,000, ~10,000, ~5,000, respectively | Caprolactone itself is a biodegradable polyester with a relatively low melting point (60C) but a glass transition temperature (Tg) around -60C. The high crystallinity in the polyester accounts for this property balance. It is made by metal catalyzed ring opening polymerization of epsilon caprolactone. A typical molecular weight of standard polycaprolactone homopolymer is 188k Daltons. By comparison. a 100% polylactic acid homopolymer with Mw 330k Daltons has a (Tg) temperature of +55C and a melting temperature. Tm of about 175C. Further modifications of polycaprolactone are possible by converting it into diblock (A-B) or triblock (A-B-A) copolymers with polyethylene glycol. Synthetic methods which lead to block structures allow the polymer to have controlled biodegradation rates as well as improved physiological compatibility characteristics. Low molecular weight PEG blocks or caprolactone blocks are tolerated in the human body and are excretable. Such amphiphilic block copolymers are also convertible into polymersomes or vesicles which may contain active compounds (API) which are released during degradation. |
| Mw of PCL, PEG, PCL is ~5,000, ~2,000, ~5,000, respectively | Caprolactone itself is a biodegradable polyester with a relatively low melting point (60C) but a glass transition temperature (Tg) around -60C. The high crystallinity in the polyester accounts for this property balance. It is made by metal catalyzed ring opening polymerization of epsilon caprolactone. A typical molecular weight of standard polycaprolactone homopolymer is 188k Daltons. By comparison. a 100% polylactic acid homopolymer with Mw 330k Daltons has a (Tg) temperature of +55C and a melting temperature. Tm of about 175C. Further modifications of polycaprolactone are possible by converting it into diblock (A-B) or triblock (A-B-A) copolymers with polyethylene glycol. Synthetic methods which lead to block structures allow the polymer to have controlled biodegradation rates as well as improved physiological compatibility characteristics. Low molecular weight PEG blocks or caprolactone blocks are tolerated in the human body and are excretable. Such amphiphilic block copolymers are also convertible into polymersomes or vesicles which may contain active compounds (API) which are released during degradation. |
| Mw of PCL, PEG, PCL is ~1,000, ~6,000, ~1,000, respectively | Caprolactone itself is a biodegradable polyester with a relatively low melting point (60C) but a glass transition temperature (Tg) around -60C. The high crystallinity in the polyester accounts for this property balance. It is made by metal catalyzed ring opening polymerization of epsilon caprolactone. A typical molecular weight of standard polycaprolactone homopolymer is 188k Daltons. By comparison. a 100% polylactic acid homopolymer with Mw 330k Daltons has a (Tg) temperature of +55C and a melting temperature. Tm of about 175C. Further modifications of polycaprolactone are possible by converting it into diblock (A-B) or triblock (A-B-A) copolymers with polyethylene glycol. Synthetic methods which lead to block structures allow the polymer to have controlled biodegradation rates as well as improved physiological compatibility characteristics. Low molecular weight PEG blocks or caprolactone blocks are tolerated in the human body and are excretable. Such amphiphilic block copolymers are also convertible into polymersomes or vesicles which may contain active compounds (API) which are released during degradation. |
| Mw of PCL, PEG, PCL is ~1,000, ~1,000, ~1,000, respectively | Caprolactone itself is a biodegradable polyester with a relatively low melting point (60C) but a glass transition temperature (Tg) around -60C. The high crystallinity in the polyester accounts for this property balance. It is made by metal catalyzed ring opening polymerization of epsilon caprolactone. A typical molecular weight of standard polycaprolactone homopolymer is 188k Daltons. By comparison. a 100% polylactic acid homopolymer with Mw 330k Daltons has a (Tg) temperature of +55C and a melting temperature. Tm of about 175C. Further modifications of polycaprolactone are possible by converting it into diblock (A-B) or triblock (A-B-A) copolymers with polyethylene glycol. Synthetic methods which lead to block structures allow the polymer to have controlled biodegradation rates as well as improved physiological compatibility characteristics. Low molecular weight PEG blocks or caprolactone blocks are tolerated in the human body and are excretable. Such amphiphilic block copolymers are also convertible into polymersomes or vesicles which may contain active compounds (API) which are released during degradation. |
| Mw of PCL, PEG, PCL is ~1,000, ~2,000, ~1,000, respectively | Caprolactone itself is a biodegradable polyester with a relatively low melting point (60C) but a glass transition temperature (Tg) around -60C. The high crystallinity in the polyester accounts for this property balance. It is made by metal catalyzed ring opening polymerization of epsilon caprolactone. A typical molecular weight of standard polycaprolactone homopolymer is 188k Daltons. By comparison. a 100% polylactic acid homopolymer with Mw 330k Daltons has a (Tg) temperature of +55C and a melting temperature. Tm of about 175C. Further modifications of polycaprolactone are possible by converting it into diblock (A-B) or triblock (A-B-A) copolymers with polyethylene glycol. Synthetic methods which lead to block structures allow the polymer to have controlled biodegradation rates as well as improved physiological compatibility characteristics. Low molecular weight PEG blocks or caprolactone blocks are tolerated in the human body and are excretable. Such amphiphilic block copolymers are also convertible into polymersomes or vesicles which may contain active compounds (API) which are released during degradation. |
