Pyrido[2,3-b]pyrazin-7-ylboronic acid, pinacol ester

Product Information

Molecular Formula:
C13H16BN3O2
Molecular Weight:
257.1
Description
Pyrido[2,3-b]pyrazin-7-ylboronic acid, pinacol ester is an indispensable compound in the realm of the biomedical sector. Its utilization revolves around the exploration of revolutionary pharmaceutical solutions, transcending the boundaries of maladies comprising cancer, diabetes, and neurodegenerative conditions. Notably, this ester derivative presents a remarkable amplitude of improved reliability, solubility, and bioavailability, serving as a promising adjunct in forging proficient drug formulation and dispensation mechanisms.
Synonyms
7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrido[2,3-b]pyrazine; 1210047-44-1; Pyrido[2,3-b]pyrazin-7-ylboronicacidpinacolester; 7-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDO[2,3-B]PYRAZINE; Pyrido[2,3-b]pyrazine-7-boronicacid,pinacolester; Pyrido[2,3-b]pyrazin-7-ylboronicacid,pinacolester
IUPAC Name
7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrido[2,3-b]pyrazine
Canonical SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC3=NC=CN=C3N=C2
InChI
InChI=1S/C13H16BN3O2/c1-12(2)13(3,4)19-14(18-12)9-7-10-11(17-8-9)16-6-5-15-10/h5-8H,1-4H3
InChI Key
QLYMAIYXJXENHJ-UHFFFAOYSA-N
Melting Point
167-172 °C
Flash Point
Not applicable
Purity
95%
Storage
2-8°C

Safety Information

Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338

Computed Properties

Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Rotatable Bond Count
1
Exact Mass
257.1335569 g/mol
Monoisotopic Mass
257.1335569 g/mol
Topological Polar Surface Area
57.1Ų
Heavy Atom Count
19
Formal Charge
0
Complexity
335
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
WO-2021249913-A9 2'-(quinolin-3-yl)-5',6'-dihydrospiro[azetidine-3,4'-pyrrolo[1,2-b]pyrazole]-1-carboxylate derivatives and related compounds as map4k1 (hpk1) inhibitors for the treatment of cancer 2020-06-09
US-2021078975-A1 Fused cyclic urea derivatives as crhr2 antagonist 2018-04-09
US-10266532-B2 Tricyclic modulators of TNF signaling 2015-04-17
US-2016304517-A1 Tricyclic modulators of tnf signaling 2015-04-17
US-2018179198-A1 Tricyclic modulators of tnf signaling 2015-04-17
US-9856253-B2 Tricyclic modulators of TNF signaling 2015-04-17
US-2014179676-A1 Heterocyclic nuclear hormone receptor modulators 2012-12-21
US-9150592-B2 Heterocyclic nuclear hormone receptor modulators 2012-12-21
US-2014045814-A1 Pyrazine derivatives as fgfr inhibitors 2012-08-10
US-2016280713-A1 Pyrazine derivatives as fgfr inhibitors 2012-08-10
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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