S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE
Product Information
Molecular Formula
C6H6O4S
Molecular Weight
174.18
Description
S-Acetylmercaptosuccinic Anhydride is a crucial chemical compound that finds extensive application within the biomedical domain. With its role as a reactant and linker, it effectively contributes to the synthesis of diverse drugs and pharmaceutical intermediates. Its versatility transcends boundaries as it influences the advancement of therapies for a wide range of ailments such as cancer, autoimmune disorders, and infectious diseases.
Synonyms
2-(ACETYLTHIO)SUCCINIC ANHYDRIDE; LABOTEST-BB LT00159681; S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE; Ethanethioicacid,S-(tetrahydro-2,5-dioxo-3-furanyl)ester; (acetylthio)succinic anhydride; (S)-Acetyl-2-mercaptosuccinicanhydride; 2-(Acetylthio)succinic anhydride,
IUPAC Name
S-(2,5-dioxooxolan-3-yl) ethanethioate
SMILES
CC(=O)SC1CC(=O)OC1=O
InChI
InChI=1S/C6H6O4S/c1-3(7)11-4-2-5(8)10-6(4)9/h4H,2H2,1H3
InChI Key
AHTFMWCHTGEJHA-UHFFFAOYSA-N
Boiling Point
354.3°C at 760 mmHg
Melting Point
83-86°C(lit.)
Flash Point
Not applicable
Purity
99%
Density
1.42g/cm3
Storage
2-8°C
Safety Information
Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338
Computed Properties
XLogP3
0.1
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Rotatable Bond Count
2
Exact Mass
173.99867984 g/mol
Monoisotopic Mass
173.99867984 g/mol
Topological Polar Surface Area
85.7Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
223
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114057992-A | Resin composition for carbon fiber molding | 2021-11-02 |
| CN-112592385-A | Artificial polypeptide composition, antibody thereof and application thereof in pathological detection | 2020-12-02 |
| CN-112694517-A | Artificial polypeptide PL, antibody thereof and application thereof in pathological detection | 2020-12-02 |
| CN-112694520-A | Artificial polypeptide HM, antibody thereof and application thereof in pathological detection | 2020-12-02 |
| CN-112694521-A | Artificial polypeptide LH, antibody thereof and application thereof in pathological detection | 2020-12-02 |
| CN-112834736-A | Pathological detection kit for detecting multiple antigens and preparation method and application thereof | 2020-12-02 |
| CN-112063291-A | Synthesis method and application of UV-cured sterilization antistatic resin material | 2020-09-22 |
| WO-2022055352-A1 | Semicarbazone-based saponin conjugate | 2020-09-10 |
| WO-2022036229-A2 | Compositions and methods for decreasing inflammation | 2020-08-14 |
| WO-2022032175-A1 | Methods for the synthesis of protein-drug conjugates | 2020-08-06 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 17696398 | 2007-09-01 | Synthesis of hyaluronan haloacetates and biology of novel cross-linker-free synthetic extracellular matrix hydrogels | Biomacromolecules |
| 16913781 | 2006-08-24 | Quenching and blinking of fluorescence of a single dye molecule bound to gold nanoparticles | The journal of physical chemistry. B |
| 16445882 | 2006-02-27 | Importance of physical vs. chemical interactions in surface shear rheology | Advances in colloid and interface science |
