Tris(4-chlorophenyl)phosphine
Product Information
Molecular Formula
C18H12Cl3P
Molecular Weight
365.62
Description
Catalyst for: Preparation of chromans and (E,E)-1,3-dienes via reaction of γ-substituted allenoates with aldehydes; Solvent-free Heck reactions. Cocatalyst in: Regioselective carbomagnesiation of terminal alkynes and enynes with alkyl Grignard reagents; Rhodium-catalyzed coordination-assisted regioselective alkenylation of aromatic C-H bonds with terminal silylacetylenes; Rhodium-catalyzed hydrogenation reactions; Platinum-catalyzed allylation reactions.
Synonyms
tris(4-chlorophenyl)phosphine; tris(4-chlorophenyl)phosphane
IUPAC Name
tris(4-chlorophenyl)phosphane
SMILES
C1=CC(=CC=C1P(C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl)Cl
InChI
InChI=1S/C18H12Cl3P/c19-13-1-7-16(8-2-13)22(17-9-3-14(20)4-10-17)18-11-5-15(21)6-12-18/h1-12H
InChI Key
IQKSLJOIKWOGIZ-UHFFFAOYSA-N
Boiling Point
427.6 °C at 760 mmHg
Melting Point
100-103 °C (lit.)
Flash Point
Not applicable
Purity
95 %
Storage
Inert atmosphere, Room Temperature
LogP
5.40500
Safety Information
Hazards
H315 - H319 - H335
Precautionary Statement
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word
Warning
Computed Properties
XLogP3
6.5
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
0
Rotatable Bond Count
3
Exact Mass
363.974220 g/mol
Monoisotopic Mass
363.974220 g/mol
Topological Polar Surface Area
0Ų
Heavy Atom Count
22
Formal Charge
0
Complexity
275
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113698431-A | Synthesis method of phosphine (III) compound | 2021-09-27 |
| CN-112898247-A | Synthetic method of furan acetate compound | 2021-03-09 |
| CN-113149882-A | Gem-difluoroolefin-pyrroline compound and preparation method and application thereof | 2021-02-05 |
| CN-112724373-A | Functional organic porous polymer and preparation method and application thereof | 2020-12-10 |
| CN-112724373-B | Functional organic porous polymer and preparation method and application thereof | 2020-12-10 |
| WO-2022025243-A1 | Polycarbonate resin composition and molded item thereof | 2020-07-31 |
| CN-113946098-A | Colored curable resin composition, color filter, and display device | 2020-07-16 |
| CN-113946100-A | Colored curable resin composition, color filter, and display device | 2020-07-16 |
| JP-2022018965-A | Color curable resin composition, color filter and display device | 2020-07-16 |
| JP-2022018966-A | Color curable resin composition, color filter and display device | 2020-07-16 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22969506 | 2012-09-01 | cis-Dichloridobis[tris-(4-chloro-phen-yl)phosphane-κP]platinum(II) acetonitrile monosolvate | Acta crystallographica. Section E, Structure reports online |
| 21579981 | 2009-12-24 | Bis{[μ-bis-(diphenyl-arsino)methane-1:2κAs:As']nona-carbonyl-1κC,2κC,3κC-[tris-(4-chloro-phen-yl)phosphine-3κP]-triangulo-triruthenium(0)} chloro-form monosolvate | Acta crystallographica. Section E, Structure reports online |
| 17268644 | 2006-12-21 | Synthesis of stable C-phosphonate analogues of Neisseria meningitidis group A capsular polysaccharide structures using modified Mitsunobu reaction conditions | Organic & biomolecular chemistry |
| 16390116 | 2006-01-11 | Palladium-catalyzed synthesis of 1-alkylphosphonium salts from 1-alkenes | Journal of the American Chemical Society |
| 1153 | 1975-12-01 | Effect of a single administration of testosterone on the immune response and lymphoid tissues in mice | Cellular immunology |
