2,2'-IMINODIBENZOIC ACID
Product Information
Molecular Formula
C14H11NO4
Molecular Weight
257.24
Description
2,2'-Iminodibenzoic Acid is a biochemical utilized in biomedical research. As an important organoboron compound, it finds use in the synthesis of pharmaceutical drugs. Its applications also include serving as a chelating agent during the treatment of certain metal poisoning cases.
Synonyms
2,2'-dicarboxyldiphenylamine; 2,2'-diphenylaminedicarboxylicacid; 2,2'-iminodi-benzoicaci; n-(o-carboxyphenyl)-anthranilicaci; vanadox; DIPHENYLAMINE-2,2'-DICARBOXYLIC ACID; 2,2'-IMINODIBENZOIC ACID; N-Cinnamoyl-o-tolylhydrorylamine
IUPAC Name
2-(2-carboxyanilino)benzoic acid
SMILES
C1=CC=C(C(=C1)C(=O)O)NC2=CC=CC=C2C(=O)O
InChI
InChI=1S/C14H11NO4/c16-13(17)9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)14(18)19/h1-8,15H,(H,16,17)(H,18,19)
InChI Key
ZFRNOTZQUGWMQN-UHFFFAOYSA-N
Melting Point
298 °C (dec.) (lit.)
Purity
0.95
Safety Information
Hazards
H315 - H319 - H335
Precautionary Statement
P302 + P352 - P305 + P351 + P338
Computed Properties
XLogP3
3.9
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
5
Rotatable Bond Count
4
Exact Mass
257.06880783 g/mol
Monoisotopic Mass
257.06880783 g/mol
Topological Polar Surface Area
86.6Ų
Heavy Atom Count
19
Formal Charge
0
Complexity
312
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113024461-A | Preparation method of 4-carboxyl acridone | 2021-03-15 |
| CN-112708302-A | Electron transport layer coating ink and preparation method and application thereof | 2020-12-29 |
| JP-2021158344-A | Light emitting elements, display devices and lighting equipment | 2020-03-27 |
| JP-2021134223-A | Perovskite-type luminescent nanoparticles | 2020-02-21 |
| CN-111019640-A | Preparation method of perovskite thin film with high stability and excellent optical properties | 2019-11-19 |
| US-2021115300-A1 | Composition and method for silicon oxide and carbon doped silicon oxide cmp | 2019-10-22 |
| WO-2021081162-A1 | Composition and method for silicon oxide and carbon doped silicon oxide cmp | 2019-10-22 |
| TW-202122523-A | Composition and method for silicon oxide and carbon doped silicon oxide cmp | 2019-10-22 |
| JP-2021050256-A | Method for producing perovskite-type luminescent nanoparticles | 2019-09-20 |
| CN-108815154-A | Hesperetin, hesperetin and enoxolone are inhibiting the application in chloride channel | 2018-08-01 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21501335 | 2011-07-01 | Entacapone promotes cAMP-dependent colonic Cl(-) secretion in rats | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society |
| 21308994 | 2011-03-01 | Cystic fibrosis transmembrane conductance regulator modulates synaptic chloride homeostasis in motoneurons of the rat spinal cord during neonatal development | Developmental neurobiology |
| 20876742 | 2010-12-01 | Regulatory mechanism underlying cyclic changes in mouse uterine bicarbonate secretion: role of estrogen | Reproduction (Cambridge, England) |
| 18760841 | 2008-10-01 | Synthesis, characterization, interaction with DNA and cytotoxicity in vitro of dinuclear Pd(II) and Pt(II) complexes dibridged by 2,2'-azanediyldibenzoic acid | Journal of inorganic biochemistry |
| 16081479 | 2005-10-15 | Disruption of CFTR chloride channel alters mechanical properties and cAMP-dependent Cl- transport of mouse aortic smooth muscle cells | The Journal of physiology |
| 16015685 | 2005-07-21 | Tetramethylpyrazine stimulates cystic fibrosis transmembrane conductance regulator-mediated anion secretion in distal colon of rodents | World journal of gastroenterology |
| 15895685 | 2005-02-01 | Syntheses and anti-inflammatory activity of diphenylamine-2,2'-dicarboxylic acid and its metal complexes | Journal of enzyme inhibition and medicinal chemistry |
| 15300895 | 2004-09-01 | Improvement of barrier function and stimulation of colonic epithelial anion secretion by Menoease Pills | World journal of gastroenterology |
| 14694153 | 2004-01-01 | Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers | Journal of the American Society of Nephrology : JASN |
| 14695481 | 2003-12-25 | Basolateral membrane mechanisms involved in ligustrazine-stimulated anion secretion in rat distal colon | Sheng li xue bao : [Acta physiologica Sinica] |
