2,6-Pyridinedicarboxylic acid
Product Information
Molecular Formula
C7H5NO4
Molecular Weight
167.12
Description
An amphoteric polar metabolite produced by many bacterial and fungal species.
Synonyms
Dipicolinic Acid
IUPAC Name
pyridine-2,6-dicarboxylic acid
SMILES
C1=CC(=NC(=C1)C(=O)O)C(=O)O
InChI
InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-5(8-4)7(11)12/h1-3H,(H,9,10)(H,11,12)
InChI Key
WJJMNDUMQPNECX-UHFFFAOYSA-N
Boiling Point
463.7 °C at 760 mmHg
Melting Point
248-250 °C (dec.)(lit.)
Flash Point
188°C
Purity
> 95 % by HPLC
Density
1.551 g/cm3
Solubility
Soluble in ethanol, methanol, DMF, DMSO
Appearance
White solid
Application
Permitted for use as an inert ingredient in non-food pesticide products.
Storage
Store at -20 °C
Refractive Index
1.62
Stability
Stable under normal temperatures and pressures.
LogP
0.47800
Vapor Pressure
2.13E-09mmHg at 25°C
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Signal Word
Danger
Computed Properties
XLogP3
0.6
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Rotatable Bond Count
2
Exact Mass
167.02185764 g/mol
Monoisotopic Mass
167.02185764 g/mol
Topological Polar Surface Area
87.5Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
184
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114106301-A | High-performance liquid crystal high-molecular polymer and preparation method and application thereof | 2021-12-22 |
| CN-114133404-A | Preparation method and application of copper-based coordination polymer with mixed valence states | 2021-12-15 |
| CN-114133993-A | Prenatal treatment composition, prenatal treatment fluid and using method of prenatal treatment fluid | 2021-12-03 |
| CN-114134323-A | Process method for separating copper and manganese and application thereof | 2021-11-30 |
| CN-113979933-A | Preparation method of 4-chloropyridine-2, 6-diformyl chloride | 2021-11-29 |
| CN-113975901-A | Preparation method of graphene composite antiviral powder and antibacterial and antiviral air filter material | 2021-11-25 |
| CN-113999802-A | Paenibacillus cucurbitae strain capable of expressing high-activity lactase | 2021-11-23 |
| CN-113861688-A | Low-dielectric polyphenylene sulfide composite material and preparation method thereof | 2021-10-28 |
| CN-113817158-A | Preparation method of high-temperature-resistant nylon resin | 2021-10-26 |
| CN-114044913-A | Metal-organic framework material and preparation method thereof | 2021-10-25 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 31678113 | 2020-01-05 | Pyridine-2,3-dicarboxylate, quinolinic acid, induces 1N4R Tau amyloid aggregation in vitro: Another evidence for the detrimental effect of the inescapable endogenous neurotoxin | Chemico-biological interactions |
| 26639393 | 2016-04-01 | Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases | Journal of hepatology |
| 23070516 | 2012-12-07 | Rational design of a fluorescent receptor for the recognition of anthrax biomarker dipicolinate | The Analyst |
| 23088412 | 2012-11-01 | Multifactorial resistance of Bacillus subtilis spores to high-energy proton radiation: role of spore structural components and the homologous recombination and non-homologous end joining DNA repair pathways | Astrobiology |
| 22776375 | 2012-10-01 | Effects of wet heat treatment on the germination of individual spores of Clostridium perfringens | Journal of applied microbiology |
| 22836165 | 2012-09-21 | High efficiency co-sensitized solar cell based on luminescent lanthanide complexes with pyridine-2,6-dicarboxylic acid ligands | Dalton transactions (Cambridge, England : 2003) |
| 22623031 | 2012-09-07 | Synthesis, crystal structure of α-Keggin heteropolymolybdates with pyridine-2,6-dicarboxylate based frameworks, and associated RhB photocatalytic degradation and 2D-IR COS tests | Dalton transactions (Cambridge, England : 2003) |
| 22706206 | 2012-09-07 | Keggin polyoxoanion supported organic-inorganic trinuclear lutetium cluster, {Na(H2O)3[Lu(pydc)(H2O)3]3}[SiW12O40]·26.5H2O | Dalton transactions (Cambridge, England : 2003) |
| 22882262 | 2012-09-01 | Evaluation of ROSCO Neo-Sensitabs for phenotypic detection and subgrouping of ESBL-, AmpC- and carbapenemase-producing Enterobacteriaceae | APMIS : acta pathologica, microbiologica, et immunologica Scandinavica |
| 22862681 | 2012-08-22 | Anion complexation and transport by isophthalamide and dipicolinamide derivatives: DNA plasmid transformation in E. coli | Journal of the American Chemical Society |
