3-(N,N-dimethyl)propane sulfonate
Product Information
Molecular Formula
C17H37NO3S
Molecular Weight
335.55
Description
It is a Zwitterionic descaling agent used for protein cleavage, used to remove target substance from solution by foam separation.
Synonyms
SDDAB; Zwittergent 3-12 Detergent; Sulfobetaine 12; Sulfobetaine 3-10; Dodecyldimethyl(3-sulfopropyl)ammonium Hydroxide; Dodecyldimethyl(3-sulfopropyl)ammonium Hydroxide Inner Salt; Dodecyldimethylammonium propanesulfonate; N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate; 3-(Dodecyldimethylammonio)propanesulfonate; 3-(Lauryldimethylammonio)propanesulfonate
IUPAC Name
3-[dodecyl(dimethyl)azaniumyl]propane-1-sulfonate
SMILES
CCCCCCCCCCCC[N+](C)(C)CCCS(=O)(=O)[O-]
InChI
InChI=1S/C17H37NO3S/c1-4-5-6-7-8-9-10-11-12-13-15-18(2,3)16-14-17-22(19,20)21/h4-17H2,1-3H3
InChI Key
IZWSFJTYBVKZNK-UHFFFAOYSA-N
Melting Point
250-260°C (dec.)
Flash Point
230 °F
Purity
≥99%
Solubility
Slightly soluble in Chloroform, Methanol
Appearance
White Crystal Powder
Application
Zwitterionic detergent.
Storage
2-8°C under inert atmosphere
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
QC Data
Computed Properties
XLogP3
5
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
14
Exact Mass
335.24941522 g/mol
Monoisotopic Mass
335.24941522 g/mol
Topological Polar Surface Area
65.6Ų
Heavy Atom Count
22
Formal Charge
0
Complexity
334
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114106627-A | Environment-friendly water-based ink and preparation method and application thereof | 2021-12-14 |
| CN-113736444-A | Preparation method of alcohol-based fracturing fluid | 2021-09-28 |
| CN-113736444-B | Preparation method of alcohol-based fracturing fluid | 2021-09-28 |
| CN-113668261-A | Dyeing liquid for optical resin and application method thereof | 2021-09-10 |
| CN-113583679-A | Ferrite surface roughening liquid and application thereof in ferrite surface roughening treatment and metallization treatment | 2021-07-27 |
| CN-113429488-A | GITR/TGF-beta dual-targeting fusion protein and application thereof | 2021-07-14 |
| CN-113322121-A | SiC third-generation power semiconductor wafer cutting liquid for new energy automobile | 2021-05-28 |
| CN-113265660-A | Etching solution and application thereof | 2021-04-30 |
| CN-113185630-A | Biodegradable salt-tolerant thickening system and preparation method and application thereof | 2021-04-22 |
| CN-112961663-A | Oil displacement type fracturing fluid system and preparation method thereof | 2021-02-07 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 33358762 | 2021-03-01 | The EyeIRR-IS assay: Development and evaluation of an in vitro assay to measure the eye irritation sub-categorization of liquid chemicals | Toxicology in vitro : an international journal published in association with BIBRA |
| 22890873 | 2012-11-12 | Functionalization of reduced graphite oxide sheets with a zwitterionic surfactant | Chemphyschem : a European journal of chemical physics and physical chemistry |
| 22170587 | 2012-04-01 | Interactions of surfactants with a water treatment protein from Moringa oleifera seeds in solution studied by zeta-potential and light scattering measurements | Biopolymers |
| 21419794 | 2011-10-01 | Purification of transcriptionally active multimeric plasmid DNA using zwitterionic detergent and carbonate apatite nano-particles | Plasmid |
| 21087027 | 2010-12-16 | Proton transport properties in zwitterion blends with Brønsted acids | The journal of physical chemistry. B |
| 19072857 | 2009-09-01 | Structural stability of hepatitis C virus envelope glycoprotein E1: effect of pH and dissociative detergents | Journal of pharmaceutical sciences |
| 19153685 | 2009-01-01 | Extraction of yeast mitochondrial membrane proteins by solubilization and detergent/polymer aqueous two-phase partitioning | Methods in molecular biology (Clifton, N.J.) |
| 17498930 | 2007-07-01 | The study of the influence of surfactant charge on alkaline hydrolysis reactions of acetylsalicylic acid (ASA) and triflusal (TFL) using spectrophotometric methods | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences |
| 17266966 | 2007-03-02 | Micellar liquid chromatography with dodecyl dimethyl betaine as an in vitro method for prediction of protein-drug binding | Journal of chromatography. A |
| 16095744 | 2005-10-10 | Rapid isolation of high quality, multimeric plasmid DNA using zwitterionic detergent | Journal of biotechnology |
