Azelaic acid
| Catalog Number | Size | Price | Stock | Quantity |
|---|---|---|---|---|
| BPM-290997 | 1 kg | $199 | In stock |
Product Information
Molecular Formula
C9H16O4
Molecular Weight
188.22
Description
Azelaic acid is a naturally occurring saturated binary carboxylic acid containing nine carbon atoms, which is an important medium and long chain dibasic acid. Azelaic acid has been used in cosmetics for a long time. It has the function of inhibiting excessive secretion of oil, removing acne and freckles, and whitening skin, and it is very safe.
Synonyms
Finacea; Anchoic acid; Azelex; Lepargylic acid; 1,7-Heptanedicarboxylic acid; Skinoren; 1,9-Nonanedioic acid; Heptanedicarboxylic acid; n-Nonanedioic acid
IUPAC Name
nonanedioic acid
SMILES
C(CCCC(=O)O)CCCC(=O)O
InChI
InChI=1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)
InChI Key
BDJRBEYXGGNYIS-UHFFFAOYSA-N
Boiling Point
286°C at 100 mmHg
Melting Point
98°C
Flash Point
210 °C (closed cup)
Purity
≥98%
Density
1.029 g/cm3
Solubility
Soluble in DMSO
Appearance
White to Cream Solid
Application
Azelaic acid could be produced by ozone cracking of unsaturated fatty acid and is commonly used in grease, cosmetics and pharmaceuticals.
Storage
Store at RT
Refractive Index
1.4303
LogP
1.88630
Vapor Pressure
0.00000001 [mmHg]
Henry's Law Constant
2.23X10-11 atm-cu m/mol at 25 °C (est)
Dissociation Constants
4.55 (at 25 °C)
Safety Information
Hazards
H319:
Causes serious eye irritation.
Causes serious eye irritation.
Precautionary Statement
P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362
Signal Word
Warning
Computed Properties
XLogP3
1.6
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
8
Exact Mass
188.10485899 g/mol
Monoisotopic Mass
188.10485899 g/mol
Topological Polar Surface Area
74.6Ų
Heavy Atom Count
13
Formal Charge
0
Complexity
147
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| EP-3763769-A1 | Method for preparing copolyamide resin and copolyamide hot-melt yarn | 2020-11-09 |
| US-10934384-B1 | Polyurethane elastomer compositions, and processes thereof | 2020-09-09 |
| US-10934385-B1 | Polyurethane elastomers, bio-additive foam compositions | 2020-09-09 |
| US-10980756-B1 | Methods of treatment | 2020-03-16 |
| US-11028217-B1 | Thermoplastic polyurethane compositions comprising nitro-substituted polyester diols | 2020-03-13 |
| EP-3842409-A1 | Method and system for refining long chain dicarboxylic acid | 2019-12-24 |
| US-2021188756-A1 | Method and system for refining long chain dicarboxylic acid | 2019-12-24 |
| EP-3842472-A1 | Process for producing a concentrated aqueous solution of a salt of a diamine and dicarboxylic acid | 2019-12-23 |
| US-2021187361-A1 | Golf ball | 2019-12-23 |
| US-2021189124-A1 | Polyamide molding compounds for hypochlorite-resistant applications | 2019-12-23 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22898471 | 2013-07-01 | Increased autoimmune responses against auto-epitopes modified by oxidative and nitrosative damage in depression: implications for the pathways to chronic depression and neuroprogression | Journal of affective disorders |
| 23571415 | 2013-06-01 | Structure-based identification of OATP1B1/3 inhibitors | Molecular pharmacology |
| 22920095 | 2012-12-01 | Newer approaches to the treatment of acne vulgaris | American journal of clinical dermatology |
| 22849351 | 2012-10-01 | Management of acne scarring, part II: a comparative review of non-laser-based, minimally invasive approaches | American journal of clinical dermatology |
| 22822212 | 2012-09-01 | Lipid profiling of the Arabidopsis hypersensitive response reveals specific lipid peroxidation and fragmentation processes: biogenesis of pimelic and azelaic acid | Plant physiology |
| 22111946 | 2012-08-01 | Effect of ionization and vehicle on skin absorption and penetration of azelaic acid | Drug development and industrial pharmacy |
| 22747347 | 2012-07-17 | Kinetic studies of heterogeneous reactions of polycyclic aromatic hydrocarbon aerosols with NO₃ radicals | Environmental science & technology |
| 22385469 | 2012-07-01 | An abietane diterpenoid is a potent activator of systemic acquired resistance | The Plant journal : for cell and molecular biology |
| 22772611 | 2012-07-01 | Newer and upcoming therapies for melasma | Indian journal of dermatology, venereology and leprology |
| 22777226 | 2012-07-01 | Optimal management of papulopustular rosacea: rationale for combination therapy | Journal of drugs in dermatology : JDD |
