CHAPS hydrate
Product Information
Molecular Formula
C32H58N2O7S · xH2O
Molecular Weight
614.88
Description
0.2 w/v of CHAPS has been used to remove cerebral endothelium by brain perfusion. 2% (w/v) CHAPS has been used as rehydration buffer along with Thiourea and Urea in protein extraction. 10 mM CHAPS has been used along with 0.15 M NaCl, Tris-Cl, pH 7.6, EDTA as lysis buffer in Western Blot analysis. CHAPS has been used as hybridization buffer in in-situ hybridization method of immature mammalian CNS.
Synonyms
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate, CHAPS
IUPAC Name
3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonatehydrate
SMILES
CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C.O
InChI
InChI=1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41)1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-/m1./s1
InChI Key
SJCUTFKCLFLIFE-JWTJKVBLSA-N
Flash Point
320 °F
Purity
≥98% (HPLC)
Appearance
Off-white solid
Storage
2-8°C
Computed Properties
Hydrogen Bond Donor Count
5
Hydrogen Bond Acceptor Count
8
Rotatable Bond Count
11
Exact Mass
632.40703805 g/mol
Monoisotopic Mass
632.40703805 g/mol
Topological Polar Surface Area
156Ų
Heavy Atom Count
43
Formal Charge
0
Complexity
1030
Isotope Atom Count
0
Defined Atom Stereocenter Count
11
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2020149740-A1 | Substituted heterocyclic compounds and their use as retinoid-related orphan receptor (ror) gamma-t inhibitors | 2019-01-15 |
| US-2020190576-A1 | Adding nucleotides during sequence detection | 2018-12-14 |
| WO-2020115083-A2 | Novel amphipols | 2018-12-03 |
| WO-2020099870-A1 | Method, solution and kit for preparing a tissue sample for 3d imaging | 2018-11-14 |
| WO-2020002806-A1 | Method for detecting and/or identifying at least one target microorganism present on a surface | 2018-06-25 |
| EP-3810790-A1 | Method for detecting and/or identifying at least one target microorganism present on a surface | 2018-06-25 |
| US-2019292222-A1 | Non-antibody high-affinity-based sample preparation, sorbent, devices and methods | 2018-03-21 |
| WO-2019183334-A1 | Non-antibody high-affinity-based sample preparation, sorbents, devices and methods | 2018-03-21 |
| EP-3769083-A1 | Non-antibody high-affinity-based sample preparation, sorbents, devices and methods | 2018-03-21 |
| WO-2019164187-A1 | Sealing/stirring-type specimen treatment device and method for operating same device | 2018-02-22 |
