Diethylmalonic acid

Product Information

Molecular Formula:
(C2H5)2C(COOH)2
Molecular Weight:
160.168
Description
Diethylmalonic acid is an indispensable compound widely utilized in the biomedical sector. Its multifarious application encompasses drug synthesis, chiefly antiviral, antimalarial, and antimicrobial drugs. Remarkably, it assumes a pivotal function in combatting ailments of serious nature, such as Alzheimer's, Parkinson's, and cancer, as it effectively hampers precise biochemical pathways.
Synonyms
2,2-diethylpropanedioic acid; Propanedioic acid, diethyl-; 3,3-Pentanedicarboxylic acid; Malonic acid, diethyl-; 2,2-Diethylmalonic acid; diethylpropanedioic acid; Diethyl malonic acid; Diathylmalonsaure; 2,2-Diethylmalonicacid; Diethylmalonic acid, 98%; 2,2-Diethylmalonic acid
IUPAC Name
2,2-diethylpropanedioic acid
Canonical SMILES
CCC(CC)(C(=O)O)C(=O)O
InChI
InChI=1S/C7H12O4/c1-3-7(4-2,5(8)9)6(10)11/h3-4H2,1-2H3,(H,8,9)(H,10,11)
InChI Key
LTMRRSWNXVJMBA-UHFFFAOYSA-N
Melting Point
129-131 °C (lit.)
Flash Point
Not applicable
Purity
0.98

Computed Properties

XLogP3
1.1
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
4
Exact Mass
160.07355886 g/mol
Monoisotopic Mass
160.07355886 g/mol
Topological Polar Surface Area
74.6Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
153
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
CN-114103377-A High-barrier heat-sealable degradable film and preparation method thereof 2021-12-14
CN-113372691-A Resin composition, reinforcing liquid, reinforcing layer, and optical protective film 2021-06-23
JP-2022040643-A Inkjet recording device and maintenance method 2020-08-31
WO-2022042873-A1 Pharmaceutically acceptable lectins derived from plants, fungi and bacteria for the treatment of sars-cov-2 infections 2020-08-27
WO-2022008088-A1 Compositions with virucidal and/or antiviral activity 2020-07-09
WO-2022008093-A1 Glucocorticoid-sparing agent 2020-07-09
JP-2022001611-A Room temperature curable organopolysiloxane compositions and articles 2020-06-19
WO-2021249667-A1 Compound for the treatment of coronaviral infections 2020-06-10
JP-2021187820-A Hydrolyzable organosilane compound and its production method 2020-06-05
WO-2021245422-A2 Metal organic framework based photocatalytic system 2020-06-05

Literatures

PMID Publication Date Title Journal
22568038 2012-03-01 Synthesis and biological studies of triazolo-/thiadiazolo-benzoxazines Acta poloniae pharmaceutica
21967289 2011-10-01 Synthesis of novel 6'-spirocyclopropyl-5'-norcarbocyclic adenosine phosphonic Acid analogues as potent anti-hiv agents Nucleosides, nucleotides & nucleic acids
21796933 2011-07-01 Synthesis of new pyrimidine derivatives with evaluation of their anti-inflammatory and analgesic activities Acta poloniae pharmaceutica
21185109 2011-02-01 Synthesis and biological activity of pyrazolothienotetrahydroisoquinoline and [1,2,4]triazolo[3,4-a]thienotetrahydroisoquinoline derivatives European journal of medicinal chemistry
22076132 2011-01-01 Transport activity of the sodium bicarbonate cotransporter NBCe1 is enhanced by different isoforms of carbonic anhydrase PloS one
22355232 2011-01-01 Optimization of Benzoisothiazole dioxide inhibitory activity of the NS5B polymerase of HCV genotype 4 using ligand-steered homological modeling, reaction-driven scaffold-hopping and Enovo workflow Bioinformation
20688561 2010-10-15 Spectroscopic, solvent influence and thermal studies of ternary copper(II) complexes of diester and dinitrogen base ligands Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
20661812 2010-08-01 Synthesis and anti-HIV evaluation of new acyclic phosphonate nucleotide analogues and their bis(SATE) derivatives Nucleosides, nucleotides & nucleic acids
21579161 2010-04-17 (3aR*,7aS*)-1-(p-Tolyl-sulfon-yl)perhydro-indol-2-one Acta crystallographica. Section E, Structure reports online
21583261 2009-05-29 Diethyl 2-[(5-meth-oxy-2-methyl-1-phenyl-sulfonyl-1H-indol-3-yl)methyl-ene]malonate Acta crystallographica. Section E, Structure reports online
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Related Products

Online Inquiry
  • Verification code
USA
  • International:
  • US & Canada (Toll free):
  • Email:
  • Fax:
UK
  • Email:
Copyright © 2025 BOC Sciences. All rights reserved.
Top
0
Inquiry Basket

We use cookies to understand how you use our site and to improve the overall user experience. This includes personalizing content and advertising. Read our Privacy Policy

Accept Cookies
x