Lithium dodecyl sulfate
Product Information
Molecular Formula
C12H25LiO4S
Molecular Weight
272.33
Description
Lithium dodecyl sulfate is a versatile compound extensively utilized in the biomedical sector. It showcases remarkable prowess as a surfactant agent. Its paramount significance lies within the realm of drug formulation, predominantly in the efficacious delivery of hydrophobic pharmaceuticals. Moreover, this compound assumes a pivotal role in the progression of analytical approaches for disease identification, exemplified by its profound implication in the identification of cancer-associated biomarkers.
Synonyms
Dodecyl lithium sulfate, Dodecyl sulfate lithium salt, Lauryl sulfate lithium salt, Lithium lauryl sulfate
IUPAC Name
lithiumdodecyl sulfate
SMILES
[Li+].CCCCCCCCCCCCOS(=O)(=O)[O-]
InChI
InChI=1S/C12H26O4S.Li/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15/h2-12H2,1H3,(H,13,14,15)/q+1/p-1
InChI Key
YFVGRULMIQXYNE-UHFFFAOYSA-M
Purity
>98.0%(T)
Appearance
White to Almost white powder to crystal
Application
Used to formulate washing-cleaning products and as a laboratory reagent.
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
12
Exact Mass
272.16335888 g/mol
Monoisotopic Mass
272.16335888 g/mol
Topological Polar Surface Area
74.8Ų
Heavy Atom Count
18
Formal Charge
0
Complexity
249
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114181932-A | Nucleic acid releasing agent and its application | 2021-12-03 |
| JP-2022017429-A | Electrode complexes, batteries, electronic devices | 2021-10-29 |
| CN-113991073-A | Preparation method of lithium sulfide electrode material | 2021-09-27 |
| CN-113528295-A | Microfluidic chip capable of carrying out multi-step time sequence reaction, microfluidic method and application thereof | 2021-09-10 |
| CN-113528295-B | Microfluidic chip capable of carrying out multi-step time sequence reaction, microfluidic method and application thereof | 2021-09-10 |
| CN-113667744-A | Gene polymorphism detection kit for rocuronium bromide metabolic marker and detection method and application thereof | 2021-09-10 |
| CN-113667745-A | Gene polymorphism detection kit for drug effect prediction of tumor necrosis factor alpha inhibitor, detection method and application thereof | 2021-09-10 |
| CN-113736874-A | Gene polymorphism detection kit for salbutamol metabolic marker, detection method and application thereof | 2021-09-10 |
| CN-113755579-A | Gene polymorphism detection kit for tacrolimus metabolic marker and detection method and application thereof | 2021-09-10 |
| CN-113755589-A | Gene polymorphism detection kit for platinum drug metabolic markers and detection method and application thereof | 2021-09-10 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22614027 | 2012-07-30 | Organo/LDH nanocomposite as an adsorbent of polycyclic aromatic hydrocarbons in water and soil-water systems | Journal of hazardous materials |
| 22498503 | 2012-05-01 | Structure and dynamics of β-lactoglobulin in complex with dodecyl sulfate and laurate: a molecular dynamics study | Biophysical chemistry |
| 22172289 | 2012-02-27 | Low frequency sonophoresis mediated transdermal and intradermal delivery of ketoprofen | International journal of pharmaceutics |
| 22309403 | 2012-02-01 | E. coli o157:H7 population reduction from alfalfa seeds with malic acid and thiamine dilauryl sulfate and quality evaluation of the resulting sprouts | Journal of food science |
| 22060013 | 2011-12-20 | Comparative studies on the crystalline to fluid phase transitions of two equimolar cationic/anionic surfactant mixtures containing dodecylsulfonate and dodecylsulfate | Langmuir : the ACS journal of surfaces and colloids |
| 22022703 | 2011-12-14 | Integrative and intermediate self-assembly of multi-walled hybrid nanotubes for catanionic biomimetics | Chemical communications (Cambridge, England) |
| 21924540 | 2011-12-01 | Interaction of a two-transmembrane-helix peptide with lipid bilayers and dodecyl sulfate micelles | Biophysical chemistry |
| 21978582 | 2011-11-30 | Organo/layered double hydroxide nanohybrids used to remove non ionic pesticides | Journal of hazardous materials |
| 21939262 | 2011-11-09 | Complexes of native ubiquitin and dodecyl sulfate illustrate the nature of hydrophobic and electrostatic interactions in the binding of proteins and surfactants | Journal of the American Chemical Society |
| 21913555 | 2011-08-01 | [Comparison of mtDNA extracting methods for common sarcosaphagous insects] | Fa yi xue za zhi |
