Nonoxinol 9
Product Information
Description
Nonoxinol 9, also called as Advantage S or Delfen Cream, belongs to the nonoxynol family of nonionic surfactants.
Synonyms
Advantage S; Advantage-S; Delfen Cream; Delfen Creams; Emulgen 911; Emulgin 913; Mertz Brand of Nonoxinol; Nonoxinol; Nonoxinol Mertz Brand; Nonoxinols; Nonoxy
Boiling Point
Very high
Melting Point
30 °C
Flash Point
470 °F
Density
1.007 at 59 °F
Solubility
Soluble to 45mg/mL in DMSO
Appearance
Colorless or light yellow viscous liquid
Application
Used as a preservative in cleaning products, polishes, antiseptics, hair dyes, spermicides, etc..
Shelf Life
2 years
Storage
Store in a cool and dry place.
Tg
solid or liquid
LogP
log Kow = 4.48 (estimated physical properties based upon 5 ethoxylates)
Vapor Pressure
6.69X10-13 mm Hg at 25 °C (estimated physical properties based upon 5 ethoxylates)
Henry's Law Constant
2.62X10-17 atm-cu m/mol at 25 °C (estimated physical properties based upon 5 ethoxylates)
Decomposition
When heated to decomposition it emits acrid smoke and irritating fumes.
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
H412:
Harmful to aquatic life with long-lasting effects.
Causes skin irritation.
H319:
Causes serious eye irritation.
H412:
Harmful to aquatic life with long-lasting effects.
Precautionary Statement
P264:
Wash thoroughly after handling.
P273:
Avoid release to the environment.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
Wash thoroughly after handling.
P273:
Avoid release to the environment.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P501:
Dispose of contents/container in accordance with local/regional/national/international regulations.
| Molecular Weight | Description |
|---|---|
| n=approx. 18 | White to Almost white wax |
| n=approx. 5 | Colorless to Light yellow clear liquid |
| n=approx. 20 | White to Almost white wax |
| n=approx. 2 | Colorless to Light yellow clear liquid |
| n=approx. 15 |
Computed Properties
XLogP3
5.5
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
11
Exact Mass
264.208930132 g/mol
Monoisotopic Mass
264.208930132 g/mol
Topological Polar Surface Area
29.5Ų
Heavy Atom Count
19
Formal Charge
0
Complexity
186
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| JP-2022031355-A | Pest control method | 2021-12-15 |
| CN-114085651-A | Mine wetting type dust suppressant and preparation method thereof | 2021-11-24 |
| JP-2022006186-A | Plant disease control method | 2021-10-28 |
| JP-2022023190-A | Plant disease control method using methyltetraprowl | 2021-10-28 |
| CN-114015312-A | Laser cutting protection material for bump wafer and preparation method and application thereof | 2021-10-26 |
| CN-113910699-A | Soft shell outdoor jacket composite fabric and preparation method thereof | 2021-10-18 |
| JP-2022001607-A | Plant disease control method using phenylpyrazole compound and phenyl compound | 2021-10-15 |
| JP-2022006179-A | Phytopathogenic microbial control composition | 2021-10-15 |
| CN-113617536-A | Collecting agent and preparation method and application thereof | 2021-09-13 |
| CN-113621445-A | Crop straw surface wax wetting and destroying preparation and using method thereof | 2021-09-09 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22486240 | 2012-12-01 | Rat sperm immobilisation effects of a protein from Ricinus communis (Linn.): an in vitro comparative study with nonoxynol-9 | Andrologia |
| 22494324 | 2012-11-01 | False positives observed on the Seratec® PSA SemiQuant Cassette Test with condom lubricants | Journal of forensic sciences |
| 22592833 | 2012-06-01 | Colposcopy: still useful in microbicide safety trials? | Sexually transmitted diseases |
| 22705737 | 2012-06-01 | In vitro susceptibility of Staphylococcus aureus strains isolated from cows with subclinical mastitis to different antimicrobial agents | Journal of veterinary science |
| 22467453 | 2012-05-15 | Direct analysis in real time mass spectrometry for analysis of sexual assault evidence | Rapid communications in mass spectrometry : RCM |
| 22359093 | 2012-05-01 | Detection of the spermicide nonoxynol-9 via GC-MS | Journal of the American Society for Mass Spectrometry |
| 22183842 | 2012-01-01 | Acceptability of optical coherence tomography and abstinence requirements among women participating in microbicide safety trials | Sexually transmitted diseases |
| 22105265 | 2011-12-01 | Optical coherence tomography compared with colposcopy for assessment of vaginal epithelial damage: a randomized controlled trial | Obstetrics and gynecology |
| 22018129 | 2011-11-01 | Mucosal integrity and inflammatory markers in the female lower genital tract as potential screening tools for vaginal microbicides | Contraception |
| 21306884 | 2011-06-15 | Spermicidal action of a protein isolated from ethanolic root extracts of Achyranthes aspera: an in vitro study | Phytomedicine : international journal of phytotherapy and phytopharmacology |
