Octaethylene glycol monododecyl ether
Product Information
Molecular Formula
C28H58O9
Molecular Weight
538.75
Description
Octaethylene glycol monododecyl ether, a non-ionic surfactant formed by the ethoxylation of dodecanol (lauryl alcohol), is a non-ionic detergent for the solubilization of membrane bound proteins, as well as the viral membranes of intact influenza viruses.
Synonyms
C12E8; 3,6,9,12,15,18,21,24-Octaoxahexatriacontan-1-ol; Dodecyloctaethyleneglycol monoether; N-Dodecyl octaethylene glycol monoether; Octaethylene Glycol Mono-N-Dodecyl Ether
IUPAC Name
2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
SMILES
CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCO
InChI
InChI=1S/C28H58O9/c1-2-3-4-5-6-7-8-9-10-11-13-30-15-17-32-19-21-34-23-25-36-27-28-37-26-24-35-22-20-33-18-16-31-14-12-29/h29H,2-28H2,1H3
InChI Key
YYELLDKEOUKVIQ-UHFFFAOYSA-N
Boiling Point
585.5±45.0°C (Predicted)
Melting Point
30°C
Purity
95%
Density
0.984-0.992 g/mL at 35°C
Solubility
Soluble in Chloroform (Slightly), Methanol (Slightly)
Appearance
White to Off-white Low-melting Solid
Storage
Store at RT under inert atmosphere
Computed Properties
XLogP3
4.1
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
9
Rotatable Bond Count
34
Exact Mass
538.40808342 g/mol
Monoisotopic Mass
538.40808342 g/mol
Topological Polar Surface Area
94.1Ų
Heavy Atom Count
37
Formal Charge
0
Complexity
389
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| KR-102313788-B1 | Detergent Composition for removing Scale and Rust of Heat Exchanger | 2021-08-31 |
| CN-112245574-A | Targeting conveying system loaded with whole-cell components and application thereof | 2020-10-23 |
| WO-2022056484-A1 | Method of treating amyloidosis | 2020-09-14 |
| WO-2022053784-A1 | Crystalline form iii of tetraacetylethylenediamine | 2020-09-09 |
| WO-2022055840-A1 | Flame retardant compositions and methods of use thereof | 2020-09-08 |
| US-2022062310-A1 | Psilocybin in patients with obsessive-compulsive disorder | 2020-09-03 |
| WO-2022051578-A1 | Psilocybin in patients with obsessive-compulsive disorder | 2020-09-03 |
| US-2022064859-A1 | Modified fiber-based materials and methods of making the same | 2020-08-28 |
| WO-2022047343-A1 | Modified fiber-based materials and methods of making the same | 2020-08-28 |
| WO-2022040397-A1 | Foamable resin composition for controlling loss circulation | 2020-08-19 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21784062 | 2011-10-01 | Characterization of cationic liposomes. Influence of the bilayer composition on the kinetics of the liposome breakdown | Chemistry and physics of lipids |
| 21641607 | 2011-09-01 | Characterization of mixed non-ionic surfactants n-octyl-β-D-thioglucoside and octaethylene-glycol monododecyl ether: micellization and microstructure | Journal of colloid and interface science |
| 21284926 | 2011-06-01 | A colorimetric assay for determination of residual detergent levels in reconstituted membrane protein preparations | Analytical biochemistry |
| 21352812 | 2011-03-25 | Bulk properties of the lipid bilayer are not essential for the thermal stability of Na,K-ATPase from shark rectal gland or pig kidney | Biochemical and biophysical research communications |
| 21909355 | 2011-01-01 | The three-dimensional distribution of αA-crystalline in rat lenses and its possible relation to transparency | PloS one |
| 20715782 | 2010-09-09 | Unraveling the Na,K-ATPase alpha(4) subunit assembling induced by large amounts of C(12)E(8) by means of small-angle X-ray scattering | The journal of physical chemistry. B |
| 20417021 | 2010-08-01 | Effects of glycerol and urea on micellization, membrane partitioning and solubilization by a non-ionic surfactant | Biophysical chemistry |
| 20004176 | 2010-01-01 | Glycyl betaine is effective in slowing down the irreversible denaturation of a detergent-solubilized membrane protein, sarcoplasmic reticulum Ca2+-ATPase (SERCA1a) | Biochemical and biophysical research communications |
| 19724139 | 2009-09-01 | Crystallization of mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum with the specific inhibitor flutolanil | Acta crystallographica. Section F, Structural biology and crystallization communications |
| 19961053 | 2009-09-01 | Solubilization and partial characterization of ouabain-insensitive Na(+)-ATPase from basolateral plasma membranes of the intestinal epithelial cells | Investigacion clinica |
