OctMAB
Product Information
Molecular Formula
C21H46BrN
Molecular Weight
392.5
Description
OctMAB is a dynamin inhibitor with IC50 value of 1.9 μM for dynamin I. It can also inhibit receptor-mediated endocytosis.
Synonyms
Octadecyltrimethylammonium bromide
IUPAC Name
trimethyl(octadecyl)azaniumbromide
SMILES
CCCCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
InChI
InChI=1S/C21H46N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(2,3)4;/h5-21H2,1-4H3;1H/q+1;/p-1
InChI Key
SZEMGTQCPRNXEG-UHFFFAOYSA-M
Melting Point
250°C (dec.)
Purity
≥95%
Appearance
White to Almost white powder to crystal
Stability
Stable. Hygroscopic. Incompatible with strong oxidizing agents. Protect from moisture.
Safety Information
Hazards
H315:
Causes skin irritation.
H319:
Causes serious eye irritation.
Causes skin irritation.
H319:
Causes serious eye irritation.
Precautionary Statement
P264:
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Wash thoroughly after handling.
P280:
Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:
IF ON SKIN:
Wash with plenty of soap and water.
P332+P313:
If skin irritation occurs:
Get medical advice/attention.
P337+P313:
If eye irritation persists:
Get medical advice/attention.
P362+P364:
Take off contaminated clothing. [As modified by IV ATP].
And wash it before reuse. [Added by IV ATP].
Computed Properties
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
17
Exact Mass
391.28136 g/mol
Monoisotopic Mass
391.28136 g/mol
Topological Polar Surface Area
0Ų
Heavy Atom Count
23
Formal Charge
0
Complexity
204
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114107966-A | Chemical composite plating method for tractor axle differential shell | 2022-01-25 |
| CN-114032682-A | Dyeing and finishing process of polyester-linen blended fabric | 2021-12-25 |
| CN-114149062-A | Bactericide for sulfate reducing bacteria in polymer-containing produced liquid and preparation method and application thereof | 2021-12-17 |
| CN-113930230-A | Thick oil viscosity reducer and preparation method thereof | 2021-12-16 |
| CN-114180545-A | Copper removal method and method for preparing iron phosphate from waste lithium iron phosphate battery core powder | 2021-12-10 |
| CN-114163862-A | Multilevel structure carbon material, preparation method thereof and anticorrosive paint | 2021-12-07 |
| CN-114086223-A | Preparation method of acid bath, copper deposit and plating homogenizing agent | 2021-12-06 |
| CN-114058133-A | Preparation method of high-creep-resistance PS material | 2021-12-02 |
| CN-114133295-A | Preparation method of magnesium intercalated montmorillonite modified biochar composite material | 2021-11-30 |
| CN-114181693-A | Cationic surfactant/DCFH-DA nano reaction system and preparation method thereof | 2021-11-26 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 20863617 | 2010-12-15 | Uranium sorption on bentonite modified by octadecyltrimethylammonium bromide | Journal of hazardous materials |
| 20571068 | 2010-07-01 | The dynamin inhibitors MiTMAB and OcTMAB induce cytokinesis failure and inhibit cell proliferation in human cancer cells | Molecular cancer therapeutics |
| 19836132 | 2010-01-15 | Effect of groups difference in surfactant on solubilization of aqueous phenol using MEUF | Journal of hazardous materials |
| 19366220 | 2009-04-21 | Electrochemical and spectroscopic study of octadecyltrimethylammonium bromide/DNA surfoplexes | Langmuir : the ACS journal of surfaces and colloids |
| 18642844 | 2008-08-27 | Effect of different wood pretreatments on the sorption-desorption of linuron and metalaxyl by woods | Journal of agricultural and food chemistry |
| 17532126 | 2008-01-15 | Influence of clay mineral structure and surfactant nature on the adsorption capacity of surfactants by clays | Journal of hazardous materials |
| 17702890 | 2007-12-01 | Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II | Molecular pharmacology |
| 17416387 | 2007-08-15 | Microstructure and structural transition in coconut oil microemulsion using semidifferential electroanalysis | Journal of colloid and interface science |
| 17418856 | 2007-07-15 | Thermal stability of octadecyltrimethylammonium bromide modified montmorillonite organoclay | Journal of colloid and interface science |
| 17320152 | 2007-05-25 | Retention of pesticides in soil columns modified in situ and ex situ with a cationic surfactant | The Science of the total environment |
