Pentadecafluorooctanoic acid ammonium salt
Product Information
Molecular Formula
C8H4F15NO2
Molecular Weight
431.10
Description
Applications: Pentadecafluorooctanoic Acid is used to produce fluoropolymers. Studies showed that Pentadecafluorooctanoic Acid exhibits a long half-life in human blood and interferes with the binding between liver-fatty acid binding protein and fatty acids. Pentadecafluorooctanoic Acid also induce hepatic peroxisome proliferation in rodents.Dangerous Goods Info: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package.
Synonyms
azanium;2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluorooctanoate
IUPAC Name
azanium;2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluorooctanoate
SMILES
C(=O)(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)[O-].[NH4+]
InChI
InChI=1S/C8HF15O2.H3N/c9-2(10,1(24)25)3(11,12)4(13,14)5(15,16)6(17,18)7(19,20)8(21,22)23;/h(H,24,25);1H3
InChI Key
YOALFLHFSFEMLP-UHFFFAOYSA-N
Boiling Point
188 °C at 760 mmHg
Melting Point
163-165 °C (dec.)
Flash Point
1,163 g/cm3
Purity
> 98.0 % (T)
Density
1.163 g/cm3
Appearance
White to almost white powder to crystal
Application
Used to polymerize fluorinated monomers.
Storage
-20 °C Freezer, Under inert atmosphere
LogP
4.76900
Vapor Pressure
0.00007 [mmHg]
Safety Information
Hazards
H302 + H332 H313 H318 H360 H362 H372 H351
Precautionary Statement
P201, P202, P260, P261, P263, P264, P270, P271, P280, P281, P301+P312, P304+P312, P304+P340, P305+P351+P338, P308+P313, P310, P312, P314, P330, P405, and P501
Signal Word
Danger
Computed Properties
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
17
Rotatable Bond Count
5
Exact Mass
431.0002508 g/mol
Monoisotopic Mass
431.0002508 g/mol
Topological Polar Surface Area
41.1Ų
Heavy Atom Count
26
Formal Charge
0
Complexity
525
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-113073543-A | Bridge support treatment process for improving corrosion resistance | 2021-03-30 |
| CN-114164706-A | Thermal paper and preparation method thereof | 2020-09-10 |
| WO-2022052498-A1 | Perfluoroether fluororubber and preparation method therefor and use thereof | 2020-09-09 |
| WO-2022042110-A1 | Modified perfluoroether fluororubber, preparation method therefor, and application thereof | 2020-08-28 |
| KR-20210131483-A | Antistatic hard coating composition and hard coating material having UV hardenability comprising the same | 2020-04-23 |
| KR-102274533-B1 | Device for polymerzation and polymerization process | 2020-03-19 |
| KR-20210110078-A | Molecular weight adjustable polymer synthetic process | 2020-02-28 |
| KR-20210110079-A | Device for polymerzation and polymerization process | 2020-02-28 |
| WO-2021172831-A1 | Process for polymerizing molecular-weight controlled polymer | 2020-02-28 |
| KR-102311012-B1 | Molecular weight adjustable polymer synthetic process | 2020-02-28 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 36436258 | 2022-12-15 | Transcriptional pathways linked to fetal and maternal hepatic dysfunction caused by gestational exposure to perfluorooctanoic acid (PFOA) or hexafluoropropylene oxide-dimer acid (HFPO-DA or GenX) in CD-1 mice | Ecotoxicology and environmental safety |
| 36115532 | 2022-12-01 | Exposure to low-dose perfluorooctanoic acid promotes hepatic steatosis and disrupts the hepatic transcriptome in mice | Molecular metabolism |
| 36214631 | 2022-11-23 | PFOA-Induced Ovotoxicity Differs Between Lean and Obese Mice With Impacts on Ovarian Reproductive and DNA Damage Sensing and Repair Proteins | Toxicological sciences : an official journal of the Society of Toxicology |
| 36152675 | 2022-11-01 | Perfluorooctanoic acid (PFOA) promotes follicular growth and alters expression of genes that regulate the cell cycle and the Hippo pathway in cultured neonatal mouse ovaries | Toxicology and applied pharmacology |
| 35346789 | 2022-06-01 | Perfluorooctanoic acid promotes proliferation of the human granulosa cell line HGrC1 and alters expression of cell cycle genes and Hippo pathway effector YAP1 | Reproductive toxicology (Elmsford, N.Y.) |
| 35066053 | 2022-05-10 | Gestational exposure to GenX induces hepatic alterations by the gut-liver axis in maternal mice: A similar mechanism as PFOA | The Science of the total environment |
| 35104888 | 2022-03-28 | Perfluorooctanoic Acid Disrupts Ovarian Steroidogenesis and Folliculogenesis in Adult Mice | Toxicological sciences : an official journal of the Society of Toxicology |
| 34958885 | 2022-03-01 | iTRAQ-based quantitative proteomics analysis of Sprague-Dawley rats liver reveals perfluorooctanoic acid-induced lipid metabolism and urea cycle dysfunction | Toxicology letters |
| 35370244 | 2022-01-01 | Perfluorooctanoic acid (PFOA) as a stimulator of estrogen receptor-negative breast cancer MDA-MB-231 cell aggressiveness: Evidence for involvement of fatty acid 2-hydroxylase (FA2H) in the stimulated cell migration | The Journal of toxicological sciences |
| 34695511 | 2021-12-01 | Transcriptional effects of binary combinations of PFAS in FaO cells | Toxicology |
