Polyglycolide
Product Information
Molecular Formula
(C2H4O3)n
Description
Polyglycolide (PGA) along with polylactide may be used to prepare a biodegradable copolymer to be used as implantations. Fabrication of biopolymer/carbon nanotube composite has been reported using PGA fiber as one of the constituents of the composite. Modified porous PGA scaffolds has been fabricated.
Synonyms
Acetic acid, 2-hydroxy-, homopolymer; Glycolic acid, polyesters; Acetic acid, hydroxy-, homopolymer; Poly(glycolic acid); Glycolic acid polymer; Hydroxyacetic acid polymer; PGA; hydroxy-aceticacihomopolymer
SMILES
C(C(=O)O)O
InChI
InChI=1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
InChI Key
AEMRFAOFKBGASW-UHFFFAOYSA-N
Boiling Point
100 °C
Melting Point
78-80 °C (alpha-modification)
Flash Point
Not applicable
Density
1.53 g/mL at 25 °C(lit.)
Appearance
Yellow to brown granular solid
Application
Used as a cheap organic acid to manufacture adhesives; to dye, print, and crease-proof textiles; to clean metals, water wells, and dairy equipment; and to delime hides and process furs; Also used in leather dyeing, adhesives, electroplating, pH control, copper pickling, printed wire board flux, oil well acidification, biodegradable polymers, soldering compounds, iron chelating, chemical milling, etching lithographic plates, and dermatology; Active product registrations for uses in cleaning products.
Storage
Store at room temperature for tech grade. Store at -20°C for pharmaceutical grade.
Stability
Stable under recommended storage conditions.
LogP
log Kow = -1.11
Vapor Pressure
0.02 [mmHg]
Henry's Law Constant
8.5X10-8 atm-cu m/mol at 25 °C (est)
Decomposition
Hazardous decomposition products formed under fire conditions. - Carbon oxides
Dissociation Constants
3.83
Odor
Odorless
Safety Information
Handling
Eyeshields, Gloves, type N95 (US)
Computed Properties
XLogP3
-1.1
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
76.016043985 g/mol
Monoisotopic Mass
76.016043985 g/mol
Topological Polar Surface Area
57.5Ų
Heavy Atom Count
5
Formal Charge
0
Complexity
40.2
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-110028627-A | Carboxymethyl cellulose graft copolymer and application thereof | 2019-03-06 |
| CN-106905488-A | A kind of preparation method of many carboxy starch composite high water absorption resins | 2017-04-12 |
| CN-106905488-B | A kind of preparation method of more carboxy starch composite high water absorption resins | 2017-04-12 |
| CN-110382553-A | Amphiphilic polysaccharide derivates and composition comprising it | 2016-12-16 |
| CN-109312003-A | Detergent composition | 2016-06-13 |
| CN-109312268-A | Detergent composition | 2016-06-13 |
| TW-201708653-A | Improved device and method | 2015-06-01 |
| US-2016200741-A1 | Novel indazoles for the treatment and prophylaxis of respiratory syncytial virus infection | 2015-01-09 |
| CN-104448742-A | High-performance anti-static filament reinforced polylactic acid composite material and preparation method thereof | 2014-12-01 |
| CN-104448742-B | High performance antistatic long fiber reinforcement lactic acid composite material and preparation method thereof | 2014-12-01 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 33688722 | 2021-03-19 | Covalent Inactivation of Mycobacterium tuberculosis Isocitrate Lyase by cis-2,3-Epoxy-Succinic Acid | ACS chemical biology |
| 33358762 | 2021-03-01 | The EyeIRR-IS assay: Development and evaluation of an in vitro assay to measure the eye irritation sub-categorization of liquid chemicals | Toxicology in vitro : an international journal published in association with BIBRA |
| 32979392 | 2020-11-15 | The effects of aliphatic alcohols and related acid metabolites in zebrafish embryos - correlations with rat developmental toxicity and with effects in advanced life stages in fish | Toxicology and applied pharmacology |
| 31711903 | 2020-01-01 | Exposure-based assessment of chemical teratogenicity using morphogenetic aggregates of human embryonic stem cells | Reproductive toxicology (Elmsford, N.Y.) |
| 29953848 | 2018-08-25 | Mechanistic-based non-animal assessment of eye toxicity: Inflammatory profile of human keratinocytes cells after exposure to eye damage/irritant agents | Chemico-biological interactions |
| 22975400 | 2012-12-01 | Large-surface mesoporous TiO2 nanoparticles: synthesis, growth and photocatalytic performance | Journal of colloid and interface science |
| 23084901 | 2012-12-01 | Prohormone-substrate peptide sequence recognition by peptidylglycine α-amidating monooxygenase and its reflection in increased glycolate inhibitor potency | Bioorganic & medicinal chemistry letters |
| 22137963 | 2012-11-01 | Advanced bacterial polyhydroxyalkanoates: towards a versatile and sustainable platform for unnatural tailor-made polyesters | Biotechnology advances |
| 22925453 | 2012-11-01 | Inside the alkalinity engine: the role of electron donors in the organomineralization potential of sulfate-reducing bacteria | Geobiology |
| 23044998 | 2012-11-01 | Review: ototoxic characteristics of platinum antitumor drugs | Anatomical record (Hoboken, N.J. : 2007) |
