TRIETHYLENE GLYCOL MONO-N-DODECYL ETHER
Product Information
Molecular Formula
C18H38O4
Molecular Weight
318.49
Description
TRIETHYLENE GLYCOL MONO-N-DODECYL ETHER is a biomedicine chemical used as a solubilizing agent in drug formulations. It can enhance drug delivery by increasing the solubility of hydrophobic drugs, making them more bioavailable. It finds utility in a wide range of pharmaceutical applications, particularly in the formulation of drugs for topical use, such as creams and ointments, as well as oral drug delivery systems.
Synonyms
POLYOXYETHYLENE 3 LAURYL ETHER; TRIETHYLENE GLYCOL MONO-N-DODECYL ETHER; TRIETHYLENE GLYCOL MONODODECYL ETHER; 2-(2-(2-(dodecyloxy)ethoxy)ethoxy)-ethano; 2-(2-(2-(dodecyloxy)ethoxy)ethoxy)ethanol; 2-(2-(2-dodecyloxyethoxy)-ethoxy)-ethanol
IUPAC Name
2-[2-(2-dodecoxyethoxy)ethoxy]ethanol
SMILES
CCCCCCCCCCCCOCCOCCOCCO
InChI
InChI=1S/C18H38O4/c1-2-3-4-5-6-7-8-9-10-11-13-20-15-17-22-18-16-21-14-12-19/h19H,2-18H2,1H3
InChI Key
FKMHSNTVILORFA-UHFFFAOYSA-N
Boiling Point
412°C at 760mmHg
Melting Point
16 °C
Flash Point
202.9°C
Purity
>95.0%(GC)
Density
0.93
Solubility
water, 13.18 mg/L @ 25 °C (est)
Appearance
solid
Storage
2-8°C
Refractive Index
n20/D 1.451
Stability
Stable. Combustible. Incompatible with strong oxidizing agents.
Computed Properties
XLogP3
4.8
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
19
Exact Mass
318.27700969 g/mol
Monoisotopic Mass
318.27700969 g/mol
Topological Polar Surface Area
47.9Ų
Heavy Atom Count
22
Formal Charge
0
Complexity
188
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114099351-A | Bioceramic gutta-percha point | 2021-12-06 |
| CN-114149712-A | Bathroom crayon and preparation method thereof | 2021-09-30 |
| CN-113616557-A | Moisturizing washing skin care product and preparation method thereof | 2021-08-20 |
| CN-113546015-A | Honeycomb hydrogel based on citrus fruit extract and preparation process thereof | 2021-07-26 |
| CN-113499284-A | Shampoo oil capable of purifying scalp hair follicles and preparation method thereof | 2021-07-09 |
| JP-2021165303-A | Pest control composition and control method | 2021-07-07 |
| JP-2021152083-A | Pest control method | 2021-07-02 |
| JP-2021152084-A | Pest control method | 2021-07-02 |
| JP-2021152085-A | Pest control method | 2021-07-02 |
| JP-2021165297-A | Pest control method | 2021-07-02 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21544841 | 2011-08-01 | Molecular dynamics simulations of ionic and nonionic surfactant micelles with a generalized Born implicit-solvent model | Journal of computational chemistry |
| 18702536 | 2008-09-16 | Self-assembly in complex mixed surfactant solutions: the impact of dodecyl triethylene glycol on dihexadecyl dimethyl ammonium bromide | Langmuir : the ACS journal of surfaces and colloids |
