Ethyl cellulose
Product Information
Description
Film-former in coatings, hot-melt adhesives and transfer inks and as a plastic coating for a variety of substrates. Ethyl cellulose is a chemically modified, non-ionic cellulose ether widely utilized in biochemical research and formulation science. Presented as a fine, free-flowing powder, it exhibits excellent solubility in organic solvents while remaining insoluble in water, making it valuable for controlled-release studies and encapsulation techniques. Its hydrophobic nature and film-forming capabilities support investigations into membrane dynamics and barrier systems. Researchers often employ ethyl cellulose in the development of sustained-release matrices and as a stabilizing agent in diverse experimental applications.
Synonyms
Cellulose ethyl ether; Ethylcellulose; Aquacoat ECD; Aqualon; Ashacel; E462; Ethocel; ethylcellulosum; Surelease
Melting Point
240-255 °C
Flash Point
Not applicable
Purity
48.0-49.5% (content of ethoxy group)
Density
1.07-1.18 g/cm3
Solubility
Soluble in Chloroform, Ethanol (95%), Ethyl Acetate, Methanol, Toluene, Glycerin (Practically), Propylene Glycol (Practically), Water (Practically)
Appearance
White to Light Tan-Colored Powder
Application
Used to make plastics, lacquers, adhesives, and wire insulation; Also used in pharmaceuticals (tablet binder), food packaging (coatings, inks, and sealing gaskets), hot-melt adhesives (cables, paper, and textiles), casings for rocket propellants, feed additive, thermoplastic molding powders and sheeting, and textile printing inks.
Storage
Store at RT
Refractive Index
n20/D 1.47 (lit.)
Stability
Stable under normal temperatures and pressures.
LogP
5.5 (LogP)
Computed Properties
XLogP3
-1.5
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
11
Rotatable Bond Count
12
Exact Mass
454.24141202 g/mol
Monoisotopic Mass
454.24141202 g/mol
Topological Polar Surface Area
135Ų
Heavy Atom Count
31
Formal Charge
0
Complexity
496
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
10
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22964399 | 2012-11-15 | Polymer coating of carrier excipients modify aerosol performance of adhered drugs used in dry powder inhalation therapy | International journal of pharmaceutics |
| 22200122 | 2012-10-01 | Preparation and in vivo evaluation of spray dried matrix type controlled-release microparticles of tamsulosin hydrochloride for orally disintegrating tablet | Drug development and industrial pharmacy |
| 23009990 | 2012-10-01 | Formulation development and investigation of ibuprofen controlled release tablets with hydrophilic polymers and the effect of co-excipients on drug release patterns | Pakistan journal of pharmaceutical sciences |
| 22698863 | 2012-09-15 | Thymol nanospheres as an effective anti-bacterial agent | International journal of pharmaceutics |
| 22528979 | 2012-08-01 | The development of thermal nanoprobe methods as a means of characterizing and mapping plasticizer incorporation into ethylcellulose films | Pharmaceutical research |
| 22561957 | 2012-08-01 | Comprehensive study of dynamic curing effect on tablet coating structure | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V |
| 22957434 | 2012-08-01 | In vitro and in vivo evaluation of novel osmotic pump tablets of isosorbide-5-mononitrate containing polyvinyl pyrrolidone (PVP) for controlled release | Die Pharmazie |
| 21222508 | 2012-07-01 | Optimization and prediction of drug release from matrix tablets using response surface methodology and near infrared chemical imaging | Pharmaceutical development and technology |
| 22525085 | 2012-07-01 | A floating multiparticulate system for ofloxacin based on a multilayer structure: In vitro and in vivo evaluation | International journal of pharmaceutics |
| 22539197 | 2012-07-01 | Study of pharmaceutical coatings by means of NMR cryoporometry and SEM image analysis | Journal of pharmaceutical sciences |
