poly-L-lysine hydrobromide

Product Information

Molecular Formula:
(6H14N2O2)x.HBr
Molecular Weight:
402.5
Description
Poly-L-lysine hydrochloride has been used to coat glass slides and coverslips to facilitate cell attachment.
Poly-lysine with mol. wt. >70,000 is useful in promoting cell adhesion to solid substrates.
Synonyms
Lysyllysyllysine; Lys-Lys-Lys; Trilysine; l-lysyl-l-lysyl-l-lysine; L-Lysine, L-lysyl-L-lysyl-; lysyl-lysyl-lysine; (S)-6-Amino-2-((S)-6-amino-2-((S)-2,6-diaminohexanamido)hexanamido)hexanoic acid; H-Lys-Lys-Lys-OH Acetate Salt; (2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]hexanoyl]amino]hexanoic acid; L-Lys-L-Lys-L-Lys-OH; L-Lysine,L-lysyl-L-lysyl-; (S)-6-Amino-2-((S)-6-amino-2-((S)-2,6-diaminohexanamido)hexanamido)hexanoicacid; N~2~-{6-Amino-2-[(2,6-diamino-1-hydroxyhexylidene)amino]-1-hydroxyhexylidene}lysine
IUPAC Name
(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]hexanoyl]amino]hexanoic acid
Canonical SMILES
C(CCN)CC(C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)N
InChI
InChI=1S/C18H38N6O4/c19-10-4-1-7-13(22)16(25)23-14(8-2-5-11-20)17(26)24-15(18(27)28)9-3-6-12-21/h13-15H,1-12,19-22H2,(H,23,25)(H,24,26)(H,27,28)/t13-,14-,15-/m0/s1
InChI Key
WBSCNDJQPKSPII-KKUMJFAQSA-N
Boiling Point
745.4°C at 760 mmHg
Flash Point
404.6°C
Purity
95%
Density
1.156 g/cm3
Appearance
white powder
Storage
2-8ºC
Stability
Stable. Incompatible with strong acids, strong bases.

Safety Information

Hazards
H315 - H317 - H319
Precautionary Statement
P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338

Computed Properties

XLogP3
-5.6
Hydrogen Bond Donor Count
7
Hydrogen Bond Acceptor Count
8
Rotatable Bond Count
17
Exact Mass
402.29545371 g/mol
Monoisotopic Mass
402.29545371 g/mol
Topological Polar Surface Area
200Ų
Heavy Atom Count
28
Formal Charge
0
Complexity
463
Isotope Atom Count
0
Defined Atom Stereocenter Count
3
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
WO-2021050568-A1 Nanoparticles for selective tissue or cellular uptake 2019-09-09
WO-2021022161-A1 Compositions and methods for treating sickle cell disease 2019-07-31
WO-2020257776-A1 Peptide nucleic acid compositions with modified hoogsteen binding segments and methods of use thereof 2019-06-21
WO-2020257779-A1 Hydroxymethyl-modified gamma-pna compositions and methods of use thereof 2019-06-21
WO-2020221896-A1 Hyaluronic acid hydrogels with prolonged antimicrobial activity 2019-05-02
EP-3797800-A1 Hyaluronic acid hydrogels with prolonged antimicrobial activity 2019-05-02
US-2021189431-A1 Compositions and methods for embryonic gene editing in vitro 2018-08-10
EP-3479851-A1 Crosslinkable polypeptide and hyaluronic acid coatings 2017-11-02
US-2020289706-A1 Crosslinkable polypeptide and hyaluronic acid coatings 2017-11-02
EP-3817784-A1 Crosslinkable polypeptide and hyaluronic acid coatings 2017-11-02
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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