Polylactic acid
Product Information
Description
Polylactic acid can be used as a filler.
Synonyms
Poly(2-hydroxypropionic acid)
SMILES
CC(C(=O)O)O
InChI
InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)
InChI Key
JVTAAEKCZFNVCJ-UHFFFAOYSA-N
Flash Point
113 °C (235 °F) - closed cup
Density
1.53 g/mL at 25 °C (lit.)
Solubility
Completely soluble in water
Appearance
Solid
Application
Used as a solvent and acidulant in the production of foods, drugs, and dyes; Also used as a mordant in woolen goods printing, a soldering flux, a dehairing agent, and a catalyst for phenolic resins; Also used in leather tanning, oil well acidizing, and as a plant growth regulator.
Storage
2-8°C
Refractive Index
1.4392 at 20 °C
Stability
Stable under recommended storage conditions.
LogP
log Kow = -0.72
Vapor Pressure
0.08 [mmHg]
Henry's Law Constant
9.6X10-9 atm-cu m/mol at 25 °C (est)
Decomposition
When heated to decompositionit emits acrid smoke and irritating fumes.
Dissociation Constants
3.86 (at 20 °C)
Odor
Odorless
Safety Information
Handling
Eyeshields, Gloves, type N95 (US)
Computed Properties
XLogP3
-0.7
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
90.031694049 g/mol
Monoisotopic Mass
90.031694049 g/mol
Topological Polar Surface Area
57.5Ų
Heavy Atom Count
6
Formal Charge
0
Complexity
59.1
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-2016264505-A1 | Bi-Component Catalyst And Method For Dehydrating Lactic Acid To Acrylic Acid | 2015-03-13 |
| US-2016264507-A1 | Method For The Dehydration Of Lactate Salt To Acrylic Acid Or Acrylic Salt | 2015-03-13 |
| CN-107466297-A | Macromolecular transition metal complex for treating cancer and preparation method thereof | 2014-12-06 |
| US-2016096827-A1 | Tank-binding kinase inhibitor compounds | 2014-09-26 |
| US-2016083326-A1 | Cost Effective Biorefining Process in Which the Product Separation Is Very Easy | 2014-09-22 |
| US-2015250884-A1 | Methods and compositions for transdermal delivery | 2014-03-10 |
| US-2015258065-A1 | Methods and compositions for transdermal delivery | 2014-03-10 |
| US-2015105584-A1 | Bio-Based Acrylic Acid And Its Derivatives | 2013-10-16 |
| US-2016193218-A1 | Novel quinazolinones as bromodomain inhibitors | 2013-07-31 |
| US-2016120985-A1 | Molecular assembly using amphipathic block polymer, and substance-conveyance carrier using same | 2013-06-12 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 36336208 | 2023-02-01 | Autophagy induces mTOR-dependent glucose uptake and mTOR-independent lactate utilization in cadmium-treated A549 cells | Toxicology in vitro : an international journal published in association with BIBRA |
| 34510316 | 2022-12-01 | Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2 | Cell biology and toxicology |
| 34418280 | 2021-11-01 | Long noncoding RNA FAM66C promotes tumor progression and glycolysis in intrahepatic cholangiocarcinoma by regulating hsa-miR-23b-3p/KCND2 axis | Environmental toxicology |
| 34382802 | 2021-08-26 | Discovery of 5-{2-[5-Chloro-2-(5-ethoxyquinoline-8-sulfonamido)phenyl]ethynyl}-4-methoxypyridine-2-carboxylic Acid, a Highly Selective in Vivo Useable Chemical Probe to Dissect MCT4 Biology | Journal of medicinal chemistry |
| 34087332 | 2021-08-15 | Triptolide impairs glycolysis by suppressing GATA4/Sp1/PFKP signaling axis in mouse Sertoli cells | Toxicology and applied pharmacology |
| 33404196 | 2021-05-01 | Puerarin prevents cadmium-induced disorder of testicular lactic acid metabolism in rats by activating 5' AMP-activated protein kinase (AMPK)/sirtuin 1 (SIRT1) signaling pathway | Environmental toxicology |
| 33596451 | 2021-04-15 | Lactate released from human fibroblasts enhances Ni elution from Ni plate | Toxicology |
| 33358762 | 2021-03-01 | The EyeIRR-IS assay: Development and evaluation of an in vitro assay to measure the eye irritation sub-categorization of liquid chemicals | Toxicology in vitro : an international journal published in association with BIBRA |
| 33038468 | 2021-02-01 | Effects of environmental metals on mitochondrial bioenergetics of the CD-1 mice pancreatic beta-cells | Toxicology in vitro : an international journal published in association with BIBRA |
| 32428594 | 2020-07-15 | Overexpression of the constitutive androstane receptor and shaken 3D-culturing increase biotransformation and oxidative phosphorylation and sensitivity to mitochondrial amiodarone toxicity of HepaRG cells | Toxicology and applied pharmacology |
