Polylactic acid

Product Information

Description
Polylactic acid can be used as a filler.
Synonyms
Poly(2-hydroxypropionic acid)
Canonical SMILES
CC(C(=O)O)O
InChI
InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)
InChI Key
JVTAAEKCZFNVCJ-UHFFFAOYSA-N
Boiling Point
122°C at 1.50E+01 mm Hg
Melting Point
16.8 °C
Flash Point
113 °C (235 °F) - closed cup
Density
1.53 g/mL at 25 °C (lit.)
Solubility
Completely soluble in water
Appearance
Solid
Application
Used as a solvent and acidulant in the production of foods, drugs, and dyes; Also used as a mordant in woolen goods printing, a soldering flux, a dehairing agent, and a catalyst for phenolic resins; Also used in leather tanning, oil well acidizing, and as a plant growth regulator.
Storage
2-8°C
Refractive Index
1.4392 at 20 °C
Stability
Stable under recommended storage conditions.
LogP
log Kow = -0.72
Vapor Pressure
0.08 [mmHg]
Henry's Law Constant
9.6X10-9 atm-cu m/mol at 25 °C (est)
Decomposition
When heated to decompositionit emits acrid smoke and irritating fumes.
Dissociation Constants
3.86 (at 20 °C)
Odor
Odorless

Safety Information

Handling
Eyeshields, Gloves, type N95 (US)

Computed Properties

XLogP3
-0.7
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
1
Exact Mass
90.031694049 g/mol
Monoisotopic Mass
90.031694049 g/mol
Topological Polar Surface Area
57.5Ų
Heavy Atom Count
6
Formal Charge
0
Complexity
59.1
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
US-2016264505-A1 Bi-Component Catalyst And Method For Dehydrating Lactic Acid To Acrylic Acid 2015-03-13
US-2016264507-A1 Method For The Dehydration Of Lactate Salt To Acrylic Acid Or Acrylic Salt 2015-03-13
CN-107466297-A Macromolecular transition metal complex for treating cancer and preparation method thereof 2014-12-06
US-2016096827-A1 Tank-binding kinase inhibitor compounds 2014-09-26
US-2016083326-A1 Cost Effective Biorefining Process in Which the Product Separation Is Very Easy 2014-09-22
US-2015250884-A1 Methods and compositions for transdermal delivery 2014-03-10
US-2015258065-A1 Methods and compositions for transdermal delivery 2014-03-10
US-2015105584-A1 Bio-Based Acrylic Acid And Its Derivatives 2013-10-16
US-2016193218-A1 Novel quinazolinones as bromodomain inhibitors 2013-07-31
US-2016120985-A1 Molecular assembly using amphipathic block polymer, and substance-conveyance carrier using same 2013-06-12

Literatures

PMID Publication Date Title Journal
36336208 2023-02-01 Autophagy induces mTOR-dependent glucose uptake and mTOR-independent lactate utilization in cadmium-treated A549 cells Toxicology in vitro : an international journal published in association with BIBRA
34510316 2022-12-01 Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2 Cell biology and toxicology
34418280 2021-11-01 Long noncoding RNA FAM66C promotes tumor progression and glycolysis in intrahepatic cholangiocarcinoma by regulating hsa-miR-23b-3p/KCND2 axis Environmental toxicology
34382802 2021-08-26 Discovery of 5-{2-[5-Chloro-2-(5-ethoxyquinoline-8-sulfonamido)phenyl]ethynyl}-4-methoxypyridine-2-carboxylic Acid, a Highly Selective in Vivo Useable Chemical Probe to Dissect MCT4 Biology Journal of medicinal chemistry
34087332 2021-08-15 Triptolide impairs glycolysis by suppressing GATA4/Sp1/PFKP signaling axis in mouse Sertoli cells Toxicology and applied pharmacology
33404196 2021-05-01 Puerarin prevents cadmium-induced disorder of testicular lactic acid metabolism in rats by activating 5' AMP-activated protein kinase (AMPK)/sirtuin 1 (SIRT1) signaling pathway Environmental toxicology
33596451 2021-04-15 Lactate released from human fibroblasts enhances Ni elution from Ni plate Toxicology
33358762 2021-03-01 The EyeIRR-IS assay: Development and evaluation of an in vitro assay to measure the eye irritation sub-categorization of liquid chemicals Toxicology in vitro : an international journal published in association with BIBRA
33038468 2021-02-01 Effects of environmental metals on mitochondrial bioenergetics of the CD-1 mice pancreatic beta-cells Toxicology in vitro : an international journal published in association with BIBRA
32428594 2020-07-15 Overexpression of the constitutive androstane receptor and shaken 3D-culturing increase biotransformation and oxidative phosphorylation and sensitivity to mitochondrial amiodarone toxicity of HepaRG cells Toxicology and applied pharmacology
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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