Pentadecanolide
Product Information
Molecular Formula
C15H28O2
Molecular Weight
240.38
Description
Pentadecanolide (CAS# 106-02-5) is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.
Synonyms
oxacyclohexadecan-2-one
IUPAC Name
oxacyclohexadecan-2-one
SMILES
C1CCCCCCCOC(=O)CCCCCC1
InChI
InChI=1S/C15H28O2/c16-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-17-15/h1-14H2
InChI Key
FKUPPRZPSYCDRS-UHFFFAOYSA-N
Boiling Point
137 °C (2 mmHg)
Melting Point
32-38 °C
Flash Point
>230 °F
Purity
95 %
Density
0.918 g/cm3
Solubility
0.1484 mg/L at 25 °C (est)
Appearance
White fine, sharp crystal
Storage
Sealed in dry, Room Temperature
Refractive Index
1.47
LogP
4.61450
Safety Information
Precautionary Statement
P261, P272, P273, P280, P302+P352, P321, P333+P313, P363, P391, and P501
Signal Word
Warning
Computed Properties
XLogP3
5.8
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
0
Exact Mass
240.208930132 g/mol
Monoisotopic Mass
240.208930132 g/mol
Topological Polar Surface Area
26.3Ų
Heavy Atom Count
17
Formal Charge
0
Complexity
189
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| JP-2022031761-A | How to improve the solubility of poorly water-soluble ingredients | 2021-11-22 |
| CN-114010543-A | Salvia officinalis sea salt essence and preparation method thereof | 2021-11-08 |
| JP-2021193141-A | Liquid composition containing lipid peptide | 2021-09-27 |
| CN-113388095-A | Modified solvent-free polyester resin and primer containing resin | 2021-08-05 |
| CN-113600012-A | High-flux high-rejection nanofiltration membrane modified by carbonic acid lactone and preparation method thereof | 2021-07-22 |
| KR-102342695-B1 | Cosmetic composition for skin soothing | 2021-07-14 |
| CN-113512300-A | High-extrusion-efficiency bamboo-based composite material containing carbon nano tubes and preparation method thereof | 2021-07-08 |
| DE-202021103593-U1 | Skin-friendly, caring and protective agent for application to the skin | 2021-07-05 |
| JP-2022023007-A | Polyurethane foam | 2021-06-30 |
| CN-113122122-A | High-solid-content polyurethane ink resin, preparation method and application thereof | 2021-04-02 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 21802477 | 2011-12-01 | Fragrance material review on ω-pentadecalactone | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association |
| 19619678 | 2010-01-01 | Scaffold for tissue engineering fabricated by non-isothermal supercritical carbon dioxide foaming of a highly crystalline polyester | Acta biomaterialia |
| 19807145 | 2009-11-09 | Enzymatic one-pot route to telechelic polypentadecalactone epoxide: synthesis, UV curing, and characterization | Biomacromolecules |
| 19632718 | 2009-10-01 | Poly(omega-pentadecalactone-co-butylene-co-succinate) nanoparticles as biodegradable carriers for camptothecin delivery | Biomaterials |
| 19966909 | 2009-01-01 | Safety and efficacy of testosterone gel in the treatment of male hypogonadism | Clinical interventions in aging |
| 18975906 | 2008-12-01 | Polymers from functional macrolactones as potential biomaterials: enzymatic ring opening polymerization, biodegradation, and biocompatibility | Biomacromolecules |
| 18939863 | 2008-11-01 | Lipase-catalyzed synthesis of aliphatic polyesters via copolymerization of lactone, dialkyl diester, and diol | Biomacromolecules |
| 18618411 | 2008-06-01 | New oxa-bridged macrocycles | Chemistry & biodiversity |
| 18198834 | 2008-02-01 | Humicola insolens cutinase-catalyzed lactone ring-opening polymerizations: kinetic and mechanistic studies | Biomacromolecules |
| 18198845 | 2008-02-01 | Lipase catalyzed HEMA initiated ring-opening polymerization: in situ formation of mixed polyester methacrylates by transesterification | Biomacromolecules |
