Poly-L-histidine
Product Information
Molecular Formula
C6H9N3O2
Molecular Weight
155.15456
Description
Poly-L-histidine has been used:• as a polycation for the dispersion of multi-wall carbon nanotubes (MWCNTs)• as a polyionic compound to investigate its ability to rupture extracellular enveloped virus membrane• in screening its anti-prion activity in cell based and in vivo anti-prion assay
Synonyms
L-histidine; histidine; 71-00-1; glyoxaline-5-alanine; L-(-)-Histidine; Anti-rheuma
IUPAC Name
2-amino-3-(1H-imidazol-5-yl)propanoic acid
SMILES
C1=C(NC=N1)CC(C(=O)O)N
InChI
InChI=1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
InChI Key
HNDVDQJCIGZPNO-YFKPBYRVSA-N
Flash Point
Not applicable
Purity
95%
Application
Histidine is an essential amino acid.
Storage
−20°C
Computed Properties
XLogP3
-3.2
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
3
Exact Mass
155.069476538 g/mol
Monoisotopic Mass
155.069476538 g/mol
Topological Polar Surface Area
92Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
151
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-11033208-B1 | Fixed operation time frequency sweeps for an analyte sensor | 2021-02-05 |
| US-11028379-B1 | FCE mRNA capping enzyme compositions, methods and kits | 2021-01-27 |
| US-11033495-B1 | Manufacturing of bupivacaine multivesicular liposomes | 2021-01-22 |
| US-11028172-B1 | Anti-TIGIT antibodies and uses thereof | 2020-11-10 |
| US-10894812-B1 | Recombinant milk proteins | 2020-09-30 |
| US-10947552-B1 | Recombinant fusion proteins for producing milk proteins in plants | 2020-09-30 |
| US-10988521-B1 | Recombinant milk proteins | 2020-09-30 |
| US-11034743-B1 | Recombinant milk proteins | 2020-09-30 |
| US-2021087539-A1 | 17Beta-HYDROXYSTEROID DEHYDROGENASE MUTANTS AND APPLICATION THEREOF | 2020-09-10 |
| US-11020475-B1 | Cold-adapted live attenuated severe acute respiratory syndrome coronavirus and vaccine containing the same | 2020-08-14 |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22794932 | 2013-01-15 | Supramolecular architecture based on the self-assembling of multiwall carbon nanotubes dispersed in polyhistidine and glucose oxidase: Characterization and analytical applications for glucose biosensing | Biosensors & bioelectronics |
| 22959184 | 2012-12-01 | Multi-arm histidine copolymer for controlled release of insulin from poly(lactide-co-glycolide) microsphere | Biomaterials |
| 22937837 | 2012-10-02 | Electrodeposition of polymer nanodots with controlled density and their reversible functionalization by polyhistidine-tag proteins | Langmuir : the ACS journal of surfaces and colloids |
| 22967133 | 2012-10-02 | Genetically encodable design of ligand 'bundling' on the surface of nanoparticles | Langmuir : the ACS journal of surfaces and colloids |
| 22076571 | 2012-09-01 | A vector design that allows fast and convenient production of differently tagged proteins | Molecular biotechnology |
| 22850858 | 2012-08-01 | The first 3':5'-cyclic nucleotide-amino acid complex: L-His-cIMP | Acta crystallographica. Section C, Crystal structure communications |
| 22681572 | 2012-07-18 | Synthesis and characterization of methylated poly(L-histidine) to control the stability of its siRNA polyion complexes for RNAi | Bioconjugate chemistry |
| 22561246 | 2012-07-01 | Purification and characterization of recombinant human endothelin receptor type A | Protein expression and purification |
| 22433465 | 2012-03-10 | Expression and purification of the cystic fibrosis transmembrane conductance regulator protein in Saccharomyces cerevisiae | Journal of visualized experiments : JoVE |
| 22108807 | 2012-03-01 | Recombinant human MDM2 oncoprotein shows sequence composition selectivity for binding to both RNA and DNA | International journal of oncology |
