Poly-L-histidine

Product Information

Molecular Formula:
C6H9N3O2
Molecular Weight:
155.15456
Description
Poly-L-histidine has been used:• as a polycation for the dispersion of multi-wall carbon nanotubes (MWCNTs)• as a polyionic compound to investigate its ability to rupture extracellular enveloped virus membrane• in screening its anti-prion activity in cell based and in vivo anti-prion assay
Synonyms
L-histidine; histidine; 71-00-1; glyoxaline-5-alanine; L-(-)-Histidine; Anti-rheuma
IUPAC Name
2-amino-3-(1H-imidazol-5-yl)propanoic acid
Canonical SMILES
C1=C(NC=N1)CC(C(=O)O)N
InChI
InChI=1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
InChI Key
HNDVDQJCIGZPNO-YFKPBYRVSA-N
Flash Point
Not applicable
Purity
95%
Application
Histidine is an essential amino acid.
Storage
−20°C

Computed Properties

XLogP3
-3.2
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
3
Exact Mass
155.069476538 g/mol
Monoisotopic Mass
155.069476538 g/mol
Topological Polar Surface Area
92Ų
Heavy Atom Count
11
Formal Charge
0
Complexity
151
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Patents

Publication Number Title Priority Date
US-11033208-B1 Fixed operation time frequency sweeps for an analyte sensor 2021-02-05
US-11028379-B1 FCE mRNA capping enzyme compositions, methods and kits 2021-01-27
US-11033495-B1 Manufacturing of bupivacaine multivesicular liposomes 2021-01-22
US-11028172-B1 Anti-TIGIT antibodies and uses thereof 2020-11-10
US-10894812-B1 Recombinant milk proteins 2020-09-30
US-10947552-B1 Recombinant fusion proteins for producing milk proteins in plants 2020-09-30
US-10988521-B1 Recombinant milk proteins 2020-09-30
US-11034743-B1 Recombinant milk proteins 2020-09-30
US-2021087539-A1 17Beta-HYDROXYSTEROID DEHYDROGENASE MUTANTS AND APPLICATION THEREOF 2020-09-10
US-11020475-B1 Cold-adapted live attenuated severe acute respiratory syndrome coronavirus and vaccine containing the same 2020-08-14

Literatures

PMID Publication Date Title Journal
22794932 2013-01-15 Supramolecular architecture based on the self-assembling of multiwall carbon nanotubes dispersed in polyhistidine and glucose oxidase: Characterization and analytical applications for glucose biosensing Biosensors & bioelectronics
22959184 2012-12-01 Multi-arm histidine copolymer for controlled release of insulin from poly(lactide-co-glycolide) microsphere Biomaterials
22937837 2012-10-02 Electrodeposition of polymer nanodots with controlled density and their reversible functionalization by polyhistidine-tag proteins Langmuir : the ACS journal of surfaces and colloids
22967133 2012-10-02 Genetically encodable design of ligand 'bundling' on the surface of nanoparticles Langmuir : the ACS journal of surfaces and colloids
22076571 2012-09-01 A vector design that allows fast and convenient production of differently tagged proteins Molecular biotechnology
22850858 2012-08-01 The first 3':5'-cyclic nucleotide-amino acid complex: L-His-cIMP Acta crystallographica. Section C, Crystal structure communications
22681572 2012-07-18 Synthesis and characterization of methylated poly(L-histidine) to control the stability of its siRNA polyion complexes for RNAi Bioconjugate chemistry
22561246 2012-07-01 Purification and characterization of recombinant human endothelin receptor type A Protein expression and purification
22433465 2012-03-10 Expression and purification of the cystic fibrosis transmembrane conductance regulator protein in Saccharomyces cerevisiae Journal of visualized experiments : JoVE
22108807 2012-03-01 Recombinant human MDM2 oncoprotein shows sequence composition selectivity for binding to both RNA and DNA International journal of oncology
The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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